Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPSH_RS00200 Genome accession   NC_010698
Coordinates   35622..36365 (+) Length   247 a.a.
NCBI ID   WP_000660503.1    Uniprot ID   -
Organism   Helicobacter pylori Shi470     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 30622..41365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSH_RS00175 (HPSH_00170) panD 32777..33127 (+) 351 WP_000142296.1 aspartate 1-decarboxylase -
  HPSH_RS00180 (HPSH_00175) - 33138..33440 (+) 303 WP_000347918.1 YbaB/EbfC family nucleoid-associated protein -
  HPSH_RS00185 (HPSH_00180) - 33440..34435 (+) 996 WP_000468449.1 PDZ domain-containing protein -
  HPSH_RS00190 (HPSH_00185) comB6 34441..35496 (+) 1056 WP_000786693.1 P-type conjugative transfer protein TrbL Machinery gene
  HPSH_RS00195 (HPSH_00190) comB7 35512..35625 (+) 114 WP_001218100.1 hypothetical protein Machinery gene
  HPSH_RS00200 (HPSH_00195) comB8 35622..36365 (+) 744 WP_000660503.1 type IV secretion system protein Machinery gene
  HPSH_RS00205 (HPSH_00200) comB9 36365..37330 (+) 966 WP_012443264.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPSH_RS00210 (HPSH_00205) comB10 37323..38459 (+) 1137 WP_001045866.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPSH_RS00215 (HPSH_00210) - 38530..39942 (+) 1413 WP_000694833.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPSH_RS00220 (HPSH_00215) gmd 39970..41115 (+) 1146 WP_000659858.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28597.83 Da        Isoelectric Point: 9.0134

>NTDB_id=30910 HPSH_RS00200 WP_000660503.1 35622..36365(+) (comB8) [Helicobacter pylori Shi470]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIFQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
VPTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=30910 HPSH_RS00200 WP_000660503.1 35622..36365(+) (comB8) [Helicobacter pylori Shi470]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAACATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGTTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTTTCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTCATGAATGAAAACAAGCTAGTTTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GTGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

95.951

100

0.96

Multiple sequence alignment