Detailed information NTG0309070

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZN22_RS07660
• Genome accession: NZ_CP031637
• Coordinates: 1499290..1500291 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS10786
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1494290..1505291

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZN22_RS07645 (DZN22_07640)	thrS	1494460..1496403 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZN22_RS07650 (DZN22_07645)	-	1496825..1498159 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZN22_RS07655 (DZN22_07650)	-	1498161..1499159 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZN22_RS07660 (DZN22_07655)	ccpA	1499290..1500291 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZN22_RS07665 (DZN22_07660)	-	1500465..1501550 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZN22_RS07670 (DZN22_07665)	-	1501599..1502264 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZN22_RS07675 (DZN22_07670)	-	1502275..1502652 (+)	378	WP_002985686.1	VOC family protein	-
DZN22_RS07680 (DZN22_07675)	-	1502797..1503723 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZN22_RS07685 (DZN22_07680)	-	1503934..1504617 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=309070 DZN22_RS07660 WP_002985680.1 1499290..1500291(-) (ccpA) [Streptococcus pyogenes strain MGAS10786]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=309070 DZN22_RS07660 WP_002985680.1 1499290..1500291(-) (ccpA) [Streptococcus pyogenes strain MGAS10786]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559