Detailed information NTG0308963

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZN63_RS07355
• Genome accession: NZ_CP031635
• Coordinates: 1470713..1471714 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS11052
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1465713..1476714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZN63_RS07340 (DZN63_07330)	thrS	1465883..1467826 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZN63_RS07345 (DZN63_07335)	-	1468248..1469582 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZN63_RS07350 (DZN63_07340)	-	1469584..1470582 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZN63_RS07355 (DZN63_07345)	ccpA	1470713..1471714 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZN63_RS07360 (DZN63_07350)	-	1471888..1472973 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZN63_RS07365 (DZN63_07355)	-	1473022..1473687 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZN63_RS07370 (DZN63_07360)	-	1473698..1474075 (+)	378	WP_002985686.1	VOC family protein	-
DZN63_RS07375 (DZN63_07365)	-	1474220..1475146 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZN63_RS07380 (DZN63_07370)	-	1475357..1476040 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308963 DZN63_RS07355 WP_002985680.1 1470713..1471714(-) (ccpA) [Streptococcus pyogenes strain MGAS11052]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308963 DZN63_RS07355 WP_002985680.1 1470713..1471714(-) (ccpA) [Streptococcus pyogenes strain MGAS11052]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559