Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EKI55_RS03050 Genome accession   NZ_CP037941
Coordinates   624482..625072 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain CFSAN027350     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 619482..630072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKI55_RS03025 (EKI55_03025) emrD 619964..621148 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  EKI55_RS29080 ysdE 621230..621304 (+) 75 WP_211180519.1 protein YsdE -
  EKI55_RS03030 (EKI55_03030) tisB 621567..621656 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EKI55_RS03035 (EKI55_03035) ivbL 622221..622319 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EKI55_RS03040 (EKI55_03040) ilvB 622425..624113 (+) 1689 WP_000168497.1 acetolactate synthase large subunit -
  EKI55_RS03045 (EKI55_03045) ilvN 624117..624407 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EKI55_RS03050 (EKI55_03050) letA 624482..625072 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EKI55_RS03055 (EKI55_03055) uhpB 625072..626574 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EKI55_RS03060 (EKI55_03060) uhpC 626584..627903 (+) 1320 WP_001341770.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EKI55_RS03065 (EKI55_03065) uhpT 628159..629550 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=308947 EKI55_RS03050 WP_000633668.1 624482..625072(+) (letA) [Escherichia coli strain CFSAN027350]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=308947 EKI55_RS03050 WP_000633668.1 624482..625072(+) (letA) [Escherichia coli strain CFSAN027350]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378