Detailed information NTG0308754

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZR09_RS07340
• Genome accession: NZ_CP031631
• Coordinates: 1454757..1455758 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28191
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1449757..1460758

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZR09_RS07325 (DZR09_07320)	thrS	1449927..1451870 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZR09_RS07330 (DZR09_07325)	-	1452292..1453626 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZR09_RS07335 (DZR09_07330)	-	1453628..1454626 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZR09_RS07340 (DZR09_07335)	ccpA	1454757..1455758 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZR09_RS07345 (DZR09_07340)	-	1455932..1457017 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZR09_RS07350 (DZR09_07345)	-	1457066..1457731 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZR09_RS07355 (DZR09_07350)	-	1457742..1458119 (+)	378	WP_002985686.1	VOC family protein	-
DZR09_RS07360 (DZR09_07355)	-	1458264..1459190 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZR09_RS07365 (DZR09_07360)	-	1459401..1460084 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308754 DZR09_RS07340 WP_002985680.1 1454757..1455758(-) (ccpA) [Streptococcus pyogenes strain MGAS28191]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308754 DZR09_RS07340 WP_002985680.1 1454757..1455758(-) (ccpA) [Streptococcus pyogenes strain MGAS28191]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559