Detailed information NTG0308593

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZS39_RS07065
• Genome accession: NZ_CP031628
• Coordinates: 1414123..1415124 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28330
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1409123..1420124

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZS39_RS07050 (DZS39_07045)	thrS	1409293..1411236 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZS39_RS07055 (DZS39_07050)	-	1411658..1412992 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZS39_RS07060 (DZS39_07055)	-	1412994..1413992 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZS39_RS07065 (DZS39_07060)	ccpA	1414123..1415124 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZS39_RS07070 (DZS39_07065)	-	1415298..1416383 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZS39_RS07075 (DZS39_07070)	-	1416432..1417097 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZS39_RS07080 (DZS39_07075)	-	1417108..1417485 (+)	378	WP_002985686.1	VOC family protein	-
DZS39_RS07085 (DZS39_07080)	-	1417630..1418556 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZS39_RS07090 (DZS39_07085)	-	1418767..1419450 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308593 DZS39_RS07065 WP_002985680.1 1414123..1415124(-) (ccpA) [Streptococcus pyogenes strain MGAS28330]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308593 DZS39_RS07065 WP_002985680.1 1414123..1415124(-) (ccpA) [Streptococcus pyogenes strain MGAS28330]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559