Detailed information NTG0308487

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZS91_RS07090
• Genome accession: NZ_CP031626
• Coordinates: 1414453..1415454 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS28386
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1409453..1420454

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZS91_RS07075 (DZS91_07070)	thrS	1409623..1411566 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZS91_RS07080 (DZS91_07075)	-	1411988..1413322 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZS91_RS07085 (DZS91_07080)	-	1413324..1414322 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZS91_RS07090 (DZS91_07085)	ccpA	1414453..1415454 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZS91_RS07095 (DZS91_07090)	-	1415628..1416713 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZS91_RS07100 (DZS91_07095)	-	1416762..1417427 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZS91_RS07105 (DZS91_07100)	-	1417438..1417815 (+)	378	WP_002985686.1	VOC family protein	-
DZS91_RS07110 (DZS91_07105)	-	1417960..1418886 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZS91_RS07115 (DZS91_07110)	-	1419097..1419780 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308487 DZS91_RS07090 WP_002985680.1 1414453..1415454(-) (ccpA) [Streptococcus pyogenes strain MGAS28386]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308487 DZS91_RS07090 WP_002985680.1 1414453..1415454(-) (ccpA) [Streptococcus pyogenes strain MGAS28386]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559