Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E0708_RS09210 Genome accession   NZ_CP037449
Coordinates   1970940..1971530 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain ATCC 25922     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1965940..1976530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0708_RS09195 (E0708_09475) uhpT 1966580..1967971 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  E0708_RS09200 (E0708_09480) uhpC 1968109..1969428 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  E0708_RS09205 (E0708_09485) uhpB 1969438..1970940 (-) 1503 WP_001304997.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  E0708_RS09210 (E0708_09490) letA 1970940..1971530 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  E0708_RS09215 (E0708_09500) - 1971945..1972805 (+) 861 WP_001259006.1 DUF6708 domain-containing protein -
  E0708_RS09220 (E0708_09505) ilvN 1972996..1973286 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  E0708_RS09225 (E0708_09510) ilvB 1973290..1974978 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  E0708_RS09230 (E0708_09515) ivbL 1975084..1975182 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  E0708_RS24620 ysdE 1975427..1975501 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=308430 E0708_RS09210 WP_000633668.1 1970940..1971530(-) (letA) [Escherichia coli strain ATCC 25922]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=308430 E0708_RS09210 WP_000633668.1 1970940..1971530(-) (letA) [Escherichia coli strain ATCC 25922]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGTTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378