Detailed information NTG0308060

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZ106_RS07360
• Genome accession: NZ_CP031618
• Coordinates: 1469561..1470562 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS29326
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1464561..1475562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZ106_RS07345 (DZ106_07335)	thrS	1464731..1466674 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZ106_RS07350 (DZ106_07340)	-	1467096..1468430 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZ106_RS07355 (DZ106_07345)	-	1468432..1469430 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZ106_RS07360 (DZ106_07350)	ccpA	1469561..1470562 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZ106_RS07365 (DZ106_07355)	-	1470736..1471821 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZ106_RS07370 (DZ106_07360)	-	1471870..1472535 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZ106_RS07375 (DZ106_07365)	-	1472546..1472923 (+)	378	WP_002985686.1	VOC family protein	-
DZ106_RS07380 (DZ106_07370)	-	1473068..1473994 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZ106_RS07385 (DZ106_07375)	-	1474205..1474888 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308060 DZ106_RS07360 WP_002985680.1 1469561..1470562(-) (ccpA) [Streptococcus pyogenes strain MGAS29326]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308060 DZ106_RS07360 WP_002985680.1 1469561..1470562(-) (ccpA) [Streptococcus pyogenes strain MGAS29326]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559