Detailed information NTG0308008

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DZ187_RS07385
• Genome accession: NZ_CP031617
• Coordinates: 1456584..1457585 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain MGAS29409
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1451584..1462585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZ187_RS07370 (DZ187_07360)	thrS	1451754..1453697 (-)	1944	WP_011284591.1	threonine--tRNA ligase	-
DZ187_RS07375 (DZ187_07365)	-	1454119..1455453 (-)	1335	WP_011284590.1	glycosyltransferase family 4 protein	-
DZ187_RS07380 (DZ187_07370)	-	1455455..1456453 (-)	999	WP_002990703.1	glycosyltransferase family 4 protein	-
DZ187_RS07385 (DZ187_07375)	ccpA	1456584..1457585 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
DZ187_RS07390 (DZ187_07380)	-	1457759..1458844 (+)	1086	WP_011284589.1	Xaa-Pro peptidase family protein	-
DZ187_RS07395 (DZ187_07385)	-	1458893..1459558 (+)	666	WP_002985684.1	NAD(P)H-dependent oxidoreductase	-
DZ187_RS07400 (DZ187_07390)	-	1459569..1459946 (+)	378	WP_002985686.1	VOC family protein	-
DZ187_RS07405 (DZ187_07395)	-	1460091..1461017 (+)	927	WP_011017477.1	glycosyltransferase family 2 protein	-
DZ187_RS07410 (DZ187_07400)	-	1461228..1461911 (+)	684	WP_011017476.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=308008 DZ187_RS07385 WP_002985680.1 1456584..1457585(-) (ccpA) [Streptococcus pyogenes strain MGAS29409]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=308008 DZ187_RS07385 WP_002985680.1 1456584..1457585(-) (ccpA) [Streptococcus pyogenes strain MGAS29409]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
TAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559