Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DV947_RS05345 Genome accession   NZ_CP031545
Coordinates   997978..999318 (-) Length   446 a.a.
NCBI ID   WP_084828862.1    Uniprot ID   A0A0E2Q0P2
Organism   Streptococcus thermophilus strain ST109     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 992978..1004318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV947_RS05315 (DV947_05320) - 993097..993483 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  DV947_RS05320 (DV947_05325) - 993541..994454 (-) 914 Protein_970 GNAT family N-acetyltransferase -
  DV947_RS05325 (DV947_05330) yidA 994662..995471 (+) 810 WP_011226081.1 sugar-phosphatase -
  DV947_RS05330 (DV947_05335) - 995473..996687 (+) 1215 WP_002953123.1 aminoacyltransferase -
  DV947_RS05335 (DV947_05340) - 996739..997100 (-) 362 Protein_973 YbaN family protein -
  DV947_RS05340 (DV947_05345) vicX 997160..997972 (-) 813 WP_116920393.1 MBL fold metallo-hydrolase Regulator
  DV947_RS05345 (DV947_05350) vicK 997978..999318 (-) 1341 WP_084828862.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DV947_RS05350 (DV947_05355) vicR 999311..1000018 (-) 708 WP_011681206.1 response regulator YycF Regulator
  DV947_RS05355 (DV947_05360) - 1000545..1001312 (+) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  DV947_RS05360 (DV947_05365) - 1001324..1002157 (+) 834 WP_116920255.1 transporter substrate-binding domain-containing protein -
  DV947_RS05365 (DV947_05370) - 1002175..1002873 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  DV947_RS05370 (DV947_05375) - 1002885..1003535 (+) 651 WP_014608375.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50777.01 Da        Isoelectric Point: 5.2465

>NTDB_id=307417 DV947_RS05345 WP_084828862.1 997978..999318(-) (vicK) [Streptococcus thermophilus strain ST109]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGQITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=307417 DV947_RS05345 WP_084828862.1 997978..999318(-) (vicK) [Streptococcus thermophilus strain ST109]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCGTAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGCAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q0P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92.825

0.686
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641

Multiple sequence alignment