Detailed information NTG0306975

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: EXA24_RS01095
• Genome accession: NZ_CP036376
• Coordinates: 186329..186790 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain Sag153
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 181329..191790

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXA24_RS01065 (EXA24_01070)	-	182944..183309 (+)	366	WP_000285373.1	DUF1033 family protein	-
EXA24_RS01070 (EXA24_01080)	comGA	183482..184453 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
EXA24_RS01075 (EXA24_01085)	comGB	184347..185390 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
EXA24_RS01080 (EXA24_01090)	comGC/cglC	185387..185716 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
EXA24_RS01085 (EXA24_01095)	comGD	185691..186104 (+)	414	WP_000244261.1	competence type IV pilus minor pilin ComGD	Machinery gene
EXA24_RS01090 (EXA24_01100)	comGE	186076..186375 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
EXA24_RS01095 (EXA24_01105)	comGF	186329..186790 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
EXA24_RS01100 (EXA24_01110)	comGG	186768..187139 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
EXA24_RS01105 (EXA24_01115)	comGH	187254..188228 (+)	975	WP_001008574.1	N-6 DNA methylase	Machinery gene
EXA24_RS01110 (EXA24_01120)	-	188260..189453 (+)	1194	WP_000047534.1	acetate kinase	-
EXA24_RS01115 (EXA24_01125)	-	189605..189811 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
EXA24_RS11335 (EXA24_01130)	-	189879..190007 (+)	129	WP_014959723.1	hypothetical protein	-
EXA24_RS01120 (EXA24_01135)	-	190048..190503 (+)	456	WP_000905673.1	hypothetical protein	-
EXA24_RS01125 (EXA24_01140)	-	190572..191237 (+)	666	WP_000008113.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=306975 EXA24_RS01095 WP_001874812.1 186329..186790(+) (comGF) [Streptococcus agalactiae strain Sag153]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=306975 EXA24_RS01095 WP_001874812.1 186329..186790(+) (comGF) [Streptococcus agalactiae strain Sag153]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373