Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   D9K49_RS07385 Genome accession   NZ_CP036202
Coordinates   1545250..1545840 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain L725     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1540250..1550840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9K49_RS07360 (D9K49_07360) emrD 1540732..1541916 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  D9K49_RS25470 ysdE 1541998..1542072 (+) 75 WP_211180519.1 protein YsdE -
  D9K49_RS07365 (D9K49_07365) tisB 1542335..1542424 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  D9K49_RS07370 (D9K49_07370) ivbL 1542989..1543087 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  D9K49_RS07375 (D9K49_07375) ilvB 1543193..1544881 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  D9K49_RS07380 (D9K49_07380) ilvN 1544885..1545175 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  D9K49_RS07385 (D9K49_07385) letA 1545250..1545840 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  D9K49_RS07390 (D9K49_07390) uhpB 1545840..1547342 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  D9K49_RS07395 (D9K49_07395) uhpC 1547352..1548671 (+) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  D9K49_RS07400 (D9K49_07400) uhpT 1548927..1550318 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=306822 D9K49_RS07385 WP_000633668.1 1545250..1545840(+) (letA) [Escherichia coli strain L725]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=306822 D9K49_RS07385 WP_000633668.1 1545250..1545840(+) (letA) [Escherichia coli strain L725]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment