Detailed information NTG0030640

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SPCG_RS10295
• Genome accession: NC_010582
• Coordinates: 1945755..1946765 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae CGSP14
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1940755..1951765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPCG_RS10270 (SPCG_1960)	-	1942101..1942394 (-)	294	WP_000977363.1	hypothetical protein	-
SPCG_RS10275 (SPCG_1961)	-	1942556..1943008 (+)	453	WP_000079148.1	universal stress protein	-
SPCG_RS10280 (SPCG_1962)	-	1943043..1944431 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
SPCG_RS10285 (SPCG_1963)	-	1944497..1945459 (+)	963	WP_001124777.1	asparaginase	-
SPCG_RS10290	-	1945488..1945691 (-)	204	WP_001813553.1	hypothetical protein	-
SPCG_RS10295 (SPCG_1964)	ccpA	1945755..1946765 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
SPCG_RS10300 (SPCG_1966)	-	1947189..1947788 (-)	600	WP_000866698.1	response regulator transcription factor	-
SPCG_RS10305 (SPCG_1967)	-	1947789..1948886 (-)	1098	WP_000893537.1	sensor histidine kinase	-
SPCG_RS10310 (SPCG_1968)	-	1948886..1949623 (-)	738	WP_001809843.1	ABC transporter permease	-
SPCG_RS10315 (SPCG_1969)	-	1949625..1950509 (-)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
SPCG_RS10320 (SPCG_1970)	-	1950496..1950690 (-)	195	WP_000820187.1	hypothetical protein	-
SPCG_RS13185	-	1950687..1950893 (-)	207	Protein_1938	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=30640 SPCG_RS10295 WP_000990607.1 1945755..1946765(-) (ccpA) [Streptococcus pneumoniae CGSP14]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=30640 SPCG_RS10295 WP_000990607.1 1945755..1946765(-) (ccpA) [Streptococcus pneumoniae CGSP14]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568