Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EW997_RS15415 Genome accession   NZ_CP035879
Coordinates   3103416..3104006 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DS26-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3098416..3109006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW997_RS15385 emrD 3098898..3100082 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  EW997_RS15390 ysdE 3100164..3100238 (+) 75 WP_211180519.1 protein YsdE -
  EW997_RS15395 tisB 3100501..3100590 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EW997_RS15400 ivbL 3101155..3101253 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EW997_RS15405 ilvB 3101359..3103047 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EW997_RS15410 ilvN 3103051..3103341 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EW997_RS15415 letA 3103416..3104006 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EW997_RS15420 uhpB 3104006..3105508 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EW997_RS15425 uhpC 3105518..3106837 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EW997_RS15430 uhpT 3106975..3108366 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=306311 EW997_RS15415 WP_000633668.1 3103416..3104006(+) (letA) [Escherichia coli strain DS26-1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=306311 EW997_RS15415 WP_000633668.1 3103416..3104006(+) (letA) [Escherichia coli strain DS26-1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378