Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EW998_RS03750 Genome accession   NZ_CP035874
Coordinates   808239..808871 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain B2C     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 803239..813871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW998_RS03725 yhfG 803371..803538 (+) 168 WP_000736860.1 YhfG family protein -
  EW998_RS03730 fic 803528..804130 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EW998_RS03735 pabA 804162..804725 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EW998_RS03740 argD 804811..806031 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EW998_RS03745 yhfK 806098..808188 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EW998_RS03750 crp 808239..808871 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EW998_RS03755 yhfA 809173..809577 (+) 405 WP_001148908.1 OsmC family protein -
  EW998_RS03760 prkB 809632..810501 (-) 870 WP_001274680.1 phosphoribulokinase -
  EW998_RS03765 yheU 810555..810773 (-) 219 WP_000907085.1 YheU family protein -
  EW998_RS03770 yheT 810767..811789 (-) 1023 WP_000057356.1 hydrolase -
  EW998_RS03775 yheS 811789..813702 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=306209 EW998_RS03750 WP_000242755.1 808239..808871(-) (crp) [Escherichia coli strain B2C]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=306209 EW998_RS03750 WP_000242755.1 808239..808871(-) (crp) [Escherichia coli strain B2C]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467