Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EW998_RS01810 Genome accession   NZ_CP035874
Coordinates   389959..390549 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain B2C     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 384959..395549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW998_RS01775 yidF 385074..385571 (+) 498 WP_000148061.1 radical SAM protein -
  EW998_RS01780 emrD 385579..386763 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  EW998_RS01785 ysdE 386845..386919 (+) 75 WP_211180519.1 protein YsdE -
  EW998_RS01790 tisB 387043..387132 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EW998_RS01795 ivbL 387697..387795 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  EW998_RS01800 ilvB 387901..389589 (+) 1689 WP_000168475.1 acetolactate synthase large subunit -
  EW998_RS01805 ilvN 389593..389883 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EW998_RS01810 letA 389959..390549 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EW998_RS01815 uhpB 390549..392051 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EW998_RS01820 uhpC 392061..393380 (+) 1320 WP_000936573.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EW998_RS01825 uhpT 393518..394909 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=306201 EW998_RS01810 WP_000633668.1 389959..390549(+) (letA) [Escherichia coli strain B2C]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=306201 EW998_RS01810 WP_000633668.1 389959..390549(+) (letA) [Escherichia coli strain B2C]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378