Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EW999_RS17930 Genome accession   NZ_CP035870
Coordinates   3671773..3672405 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain E2528-C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3666773..3677405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW999_RS17905 yhfG 3666905..3667072 (+) 168 WP_000736860.1 YhfG family protein -
  EW999_RS17910 fic 3667062..3667664 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EW999_RS17915 pabA 3667696..3668259 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EW999_RS17920 argD 3668345..3669565 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EW999_RS17925 yhfK 3669632..3671722 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EW999_RS17930 crp 3671773..3672405 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EW999_RS17935 yhfA 3672707..3673111 (+) 405 WP_001148908.1 OsmC family protein -
  EW999_RS17940 prkB 3673166..3674035 (-) 870 WP_001274680.1 phosphoribulokinase -
  EW999_RS17945 yheU 3674089..3674307 (-) 219 WP_000907085.1 YheU family protein -
  EW999_RS17950 yheT 3674301..3675323 (-) 1023 WP_000057356.1 hydrolase -
  EW999_RS17955 yheS 3675323..3677236 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=306161 EW999_RS17930 WP_000242755.1 3671773..3672405(-) (crp) [Escherichia coli strain E2528-C1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=306161 EW999_RS17930 WP_000242755.1 3671773..3672405(-) (crp) [Escherichia coli strain E2528-C1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467