Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EW999_RS16265 Genome accession   NZ_CP035870
Coordinates   3297633..3298223 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain E2528-C1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3292633..3303223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW999_RS16230 yidF 3292748..3293245 (+) 498 WP_000148076.1 radical SAM protein -
  EW999_RS16235 emrD 3293253..3294437 (-) 1185 WP_001735885.1 multidrug efflux MFS transporter EmrD -
  EW999_RS16240 ysdE 3294519..3294593 (+) 75 WP_211180519.1 protein YsdE -
  EW999_RS16245 tisB 3294717..3294806 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EW999_RS16250 ivbL 3295371..3295469 (+) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  EW999_RS16255 ilvB 3295575..3297263 (+) 1689 WP_005764012.1 acetolactate synthase large subunit -
  EW999_RS16260 ilvN 3297267..3297557 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EW999_RS16265 letA 3297633..3298223 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EW999_RS16270 uhpB 3298223..3299725 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EW999_RS16275 uhpC 3299735..3301054 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EW999_RS16280 uhpT 3301192..3302583 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=306153 EW999_RS16265 WP_000633668.1 3297633..3298223(+) (letA) [Escherichia coli strain E2528-C1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=306153 EW999_RS16265 WP_000633668.1 3297633..3298223(+) (letA) [Escherichia coli strain E2528-C1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378