Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXE34_RS22595 Genome accession   NZ_CP035865
Coordinates   4606200..4606790 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain E275 a     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4601200..4611790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXE34_RS22580 uhpT 4601840..4603231 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EXE34_RS22585 uhpC 4603369..4604688 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EXE34_RS22590 uhpB 4604698..4606200 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EXE34_RS22595 letA 4606200..4606790 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EXE34_RS22600 ilvN 4606866..4607156 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  EXE34_RS22605 ilvB 4607160..4608848 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  EXE34_RS22610 ivbL 4608954..4609052 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EXE34_RS22615 tisB 4609617..4609706 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EXE34_RS22620 ysdE 4609830..4609904 (-) 75 WP_211180519.1 protein YsdE -
  EXE34_RS22625 emrD 4609986..4611170 (+) 1185 WP_063091335.1 multidrug efflux MFS transporter EmrD -
  EXE34_RS22630 yidF 4611178..4611675 (-) 498 WP_000148061.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=306089 EXE34_RS22595 WP_000633668.1 4606200..4606790(-) (letA) [Escherichia coli strain E275 a]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=306089 EXE34_RS22595 WP_000633668.1 4606200..4606790(-) (letA) [Escherichia coli strain E275 a]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment