Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EXE34_RS20810 Genome accession   NZ_CP035865
Coordinates   4206211..4206843 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain E275 a     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4201211..4211843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXE34_RS20785 yheS 4201380..4203293 (+) 1914 WP_159382432.1 ABC transporter ATP-binding protein -
  EXE34_RS20790 yheT 4203293..4204315 (+) 1023 WP_159382433.1 hydrolase -
  EXE34_RS20795 yheU 4204309..4204527 (+) 219 WP_000907085.1 YheU family protein -
  EXE34_RS20800 prkB 4204581..4205450 (+) 870 WP_001274680.1 phosphoribulokinase -
  EXE34_RS20805 yhfA 4205505..4205909 (-) 405 WP_001148908.1 OsmC family protein -
  EXE34_RS20810 crp 4206211..4206843 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EXE34_RS20815 yhfK 4206894..4208984 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EXE34_RS20820 argD 4209051..4210271 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EXE34_RS20825 pabA 4210357..4210920 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EXE34_RS20830 fic 4210952..4211554 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EXE34_RS20835 yhfG 4211544..4211711 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=306079 EXE34_RS20810 WP_000242755.1 4206211..4206843(+) (crp) [Escherichia coli strain E275 a]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=306079 EXE34_RS20810 WP_000242755.1 4206211..4206843(+) (crp) [Escherichia coli strain E275 a]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467