Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DV166_RS06110 Genome accession   NZ_CP031334
Coordinates   1032416..1033276 (-) Length   286 a.a.
NCBI ID   WP_002226036.1    Uniprot ID   A0A112F5U3
Organism   Neisseria meningitidis strain M22293     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1027416..1038276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV166_RS06070 ispB 1027902..1028876 (+) 975 WP_002220270.1 octaprenyl diphosphate synthase -
  DV166_RS06075 - 1028881..1029327 (+) 447 WP_002220271.1 DUF441 domain-containing protein -
  DV166_RS06095 pilF 1029819..1031495 (+) 1677 WP_002231695.1 type IV-A pilus assembly ATPase PilB Machinery gene
  DV166_RS06100 - 1031580..1031789 (-) 210 WP_002226982.1 DNA gyrase inhibitor YacG -
  DV166_RS06105 coaE 1031782..1032414 (-) 633 WP_002226983.1 dephospho-CoA kinase -
  DV166_RS06110 pilD 1032416..1033276 (-) 861 WP_002226036.1 A24 family peptidase Machinery gene
  DV166_RS06115 pilG 1033350..1034582 (-) 1233 WP_002216405.1 type 4 pilus assembly protein PilG Machinery gene
  DV166_RS06125 pgi 1035092..1036735 (+) 1644 WP_115437013.1 glucose-6-phosphate isomerase -
  DV166_RS06130 - 1036705..1036935 (+) 231 WP_019742712.1 hypothetical protein -
  DV166_RS06135 dapD 1036945..1037766 (+) 822 WP_002224875.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31389.43 Da        Isoelectric Point: 8.2213

>NTDB_id=305977 DV166_RS06110 WP_002226036.1 1032416..1033276(-) (pilD) [Neisseria meningitidis strain M22293]
MSDLSVLSPFAVPLTAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=305977 DV166_RS06110 WP_002226036.1 1032416..1033276(-) (pilD) [Neisseria meningitidis strain M22293]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGACAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)

Type IV leader peptidase family (Peptidase_A24)

(134-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A112F5U3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

95.789

99.65

0.955
  pilD Vibrio cholerae strain A1552

44.097

100

0.444
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434
  pilD Vibrio campbellii strain DS40M4

44.565

96.503

0.43

Multiple sequence alignment