Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV143_RS13795 Genome accession   NZ_CP031333
Coordinates   1637427..1637891 (+) Length   154 a.a.
NCBI ID   WP_162467384.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M18727     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1637979..1649325 1637427..1637891 flank 88


Gene organization within MGE regions


Location: 1637427..1649325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV143_RS13795 comE 1637427..1637891 (+) 465 WP_162467384.1 ComEA family DNA-binding protein Machinery gene
  DV143_RS09805 comP 1637979..1638428 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  DV143_RS14385 - 1638589..1638912 (-) 324 WP_202052896.1 5'-nucleotidase -
  DV143_RS14115 - 1639043..1639195 (-) 153 WP_002223150.1 hypothetical protein -
  DV143_RS09825 - 1639552..1640196 (+) 645 WP_002223148.1 hypothetical protein -
  DV143_RS09830 - 1640212..1641303 (+) 1092 WP_002223147.1 XRE family transcriptional regulator -
  DV143_RS09835 - 1641336..1644050 (-) 2715 WP_341801439.1 DUF3418 domain-containing protein -
  DV143_RS14645 - 1644141..1644719 (-) 579 Protein_1604 ATP-dependent helicase -
  DV143_RS09840 lpt3 1644821..1646398 (-) 1578 Protein_1605 lipooligosaccharide phosphoethanolamine transferase -
  DV143_RS09850 - 1647429..1647638 (-) 210 WP_061732571.1 hypothetical protein -
  DV143_RS09855 - 1647682..1649325 (-) 1644 WP_002223143.1 AAA family ATPase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16501.79 Da        Isoelectric Point: 10.9585

>NTDB_id=305955 DV143_RS13795 WP_162467384.1 1637427..1637891(+) (comE) [Neisseria meningitidis strain M18727]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPAIPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=305955 DV143_RS13795 WP_162467384.1 1637427..1637891(+) (comE) [Neisseria meningitidis strain M18727]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTATACCGGCCGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment