Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   DV143_RS09805 Genome accession   NZ_CP031333
Coordinates   1637979..1638428 (+) Length   149 a.a.
NCBI ID   WP_002214937.1    Uniprot ID   A0AA44U8B7
Organism   Neisseria meningitidis strain M18727     
Function   DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1637979..1649325 1637979..1638428 within 0


Gene organization within MGE regions


Location: 1637979..1649325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV143_RS09805 comP 1637979..1638428 (+) 450 WP_002214937.1 type IV pilin protein Machinery gene
  DV143_RS14385 - 1638589..1638912 (-) 324 WP_202052896.1 5'-nucleotidase -
  DV143_RS14115 - 1639043..1639195 (-) 153 WP_002223150.1 hypothetical protein -
  DV143_RS09825 - 1639552..1640196 (+) 645 WP_002223148.1 hypothetical protein -
  DV143_RS09830 - 1640212..1641303 (+) 1092 WP_002223147.1 XRE family transcriptional regulator -
  DV143_RS09835 - 1641336..1644050 (-) 2715 WP_341801439.1 DUF3418 domain-containing protein -
  DV143_RS14645 - 1644141..1644719 (-) 579 Protein_1604 ATP-dependent helicase -
  DV143_RS09840 lpt3 1644821..1646398 (-) 1578 Protein_1605 lipooligosaccharide phosphoethanolamine transferase -
  DV143_RS09850 - 1647429..1647638 (-) 210 WP_061732571.1 hypothetical protein -
  DV143_RS09855 - 1647682..1649325 (-) 1644 WP_002223143.1 AAA family ATPase -

Sequence

Protein


Download         Length: 149 a.a.        Molecular weight: 16834.81 Da        Isoelectric Point: 9.7951

>NTDB_id=305937 DV143_RS09805 WP_002214937.1 1637979..1638428(+) (comP) [Neisseria meningitidis strain M18727]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide


Download         Length: 450 bp        

>NTDB_id=305937 DV143_RS09805 WP_002214937.1 1637979..1638428(+) (comP) [Neisseria meningitidis strain M18727]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGGTTTAAACAAACATCTACCAAGTGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS)

(28-107)

Prokaryotic N-terminal methylation motif (N_methyl)

(1-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Neisseria gonorrhoeae MS11

100

100

1
  comP Neisseria meningitidis 8013

99.329

100

0.993
  comP Neisseria subflava NJ9703

49.66

98.658

0.49

Multiple sequence alignment