Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV179_RS12980 Genome accession   NZ_CP031331
Coordinates   2166889..2169918 (-) Length   1009 a.a.
NCBI ID   WP_322114704.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M26263     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2161889..2174918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV179_RS12925 - 2162187..2162750 (-) 564 WP_002214615.1 phosphoribosyltransferase family protein -
  DV179_RS13930 - 2163157..2163324 (-) 168 WP_153312129.1 hypothetical protein -
  DV179_RS12935 - 2163328..2163717 (-) 390 WP_002221514.1 endonuclease domain-containing protein -
  DV179_RS12950 - 2164297..2164434 (-) 138 WP_002214606.1 VOC family protein -
  DV179_RS12955 carA 2164480..2165613 (-) 1134 WP_002217954.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  DV179_RS12980 pilC 2166889..2169918 (-) 3030 WP_322114704.1 PilC family type IV pilus tip adhesin Machinery gene
  DV179_RS14675 pilC 2169885..2170013 (-) 129 WP_306821904.1 hypothetical protein Machinery gene
  DV179_RS12990 apbC 2170815..2171894 (-) 1080 WP_024465095.1 iron-sulfur cluster carrier protein ApbC -
  DV179_RS13000 - 2172259..2172768 (+) 510 WP_002233029.1 protein disulfide oxidoreductase -
  DV179_RS13010 nadR 2173109..2173549 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  DV179_RS13015 hpaC 2173664..2174164 (+) 501 WP_024465094.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  DV179_RS13020 murU 2174182..2174877 (+) 696 WP_002237354.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1009 a.a.        Molecular weight: 110335.63 Da        Isoelectric Point: 9.5513

>NTDB_id=305902 DV179_RS12980 WP_322114704.1 2166889..2169918(-) (pilC) [Neisseria meningitidis strain M26263]
MAQTRQYAIIMNEGNQPEVQWNRSYSIKDKDRKREYTHHNHQQGGSSVSFNNSDELVSRQSGTAVFGTATYLPPYGKVSG
FDAAALKERNNAVDWIHTTHPGLIGYSYDGVVCRSATDCPKLVYKTRFSFDNPDLAKTGGGLDRHTEPSRDNSPIYKLKD
YPWLGVSFNLGAEGAAKNGKTINKLVSSFDEKNKNSNNNLVYTTEGRDISLGDWQRESTAMAYYLNAKLHLLDKKQIQNI
TDKTVQLGVLRPSIDVKTQKTGLAGILAYWARWDIKDDGQIPVKLGLQQVKAGRCVNKNNPNPNAKAPSPALTAPALWFG
PVQNGKAEMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSASDIQSKEPNFTGRQTIIRLDGGVREIKLNRS
NEATGLNGNDGKNETFGIVSEGSFMPDTSEWKKVLLPWTVRGFADDSKFKEFNKEEKNNDNKPKYSQKYRSRDNGKHERN
LGDIVNSPIVAVGGYLATSANDGMVHIFKKGNGGDERNYSLKLSYIPGTMPRKNIENNDSTLAKELRAFAEKGYVGDRYG
VDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLTKADSNNPTAVSLFDVKNDKNSNNGVELGYTVGTPQIGKTHNG
KYAAFLASGYATKEITSGDNKTALYVYDLEGNGTNNLIKKIEVPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFD
LSSQDPKQWSARAIFKGDKPITSAPAISQLKDKRVVIFGTGSDLSEDDVLSTSEQYIYGIFDDDTAASNVDVKLKGLGGG
LLEQVLEQKDKTLFLTDYKRSDGSGNKGWVVKLKDGQRVTVKPTVVLRTAFVTIHKYTGTDKCGAETAILGINTADGGKL
TKKSARPIVPEANQAVAQYSGHKKTANGKSIPIGCMQKGNETVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGI
DPAGKRSGKNNRCFSQKGVRTLLMNDLDSLDITGPMCGMKRISWREVFF

Nucleotide


Download         Length: 3030 bp        

>NTDB_id=305902 DV179_RS12980 WP_322114704.1 2166889..2169918(-) (pilC) [Neisseria meningitidis strain M26263]
ATGGCGCAAACCCGTCAATACGCTATTATCATGAACGAGGGAAACCAGCCCGAGGTACAGTGGAATAGGTCATATTCAAT
AAAGGACAAAGACAGGAAGCGCGAATATACTCATCATAATCACCAACAAGGAGGAAGCTCTGTCTCATTCAACAATAGCG
ATGAGCTTGTTTCTCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAAGGTTTCCGGT
TTTGATGCCGCCGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCACCCAGGGTTGATAGGCTACAG
CTACGACGGTGTCGTATGCAGAAGCGCCACAGACTGTCCCAAACTTGTCTATAAAACCCGATTTTCCTTCGATAATCCCG
ACTTGGCAAAAACAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCCCATTTACAAATTGAAGGAT
TATCCATGGTTGGGCGTGTCTTTCAATTTGGGTGCCGAGGGTGCCGCCAAAAATGGTAAGACAATCAACAAATTGGTATC
TTCTTTTGATGAAAAGAATAAGAATAGTAATAACAACCTCGTCTATACCACGGAAGGCCGCGATATTTCCTTGGGCGACT
GGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGAACGCCAAGCTGCACCTGCTGGATAAAAAACAGATTCAAAATATC
ACCGACAAAACAGTGCAGTTGGGTGTCTTGAGGCCGAGCATCGATGTGAAGACACAAAAGACGGGGCTTGCCGGCATTCT
AGCTTATTGGGCTAGGTGGGACATTAAAGATGACGGGCAGATTCCAGTCAAGCTCGGCCTGCAGCAAGTCAAAGCAGGCC
GCTGCGTCAACAAAAATAACCCCAATCCCAATGCCAAAGCCCCTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTTCGGC
CCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTTTCCT
GCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTGCGTCGGATATTCAAA
GTAAAGAGCCGAATTTCACGGGGCGGCAAACAATCATCCGATTGGATGGCGGCGTACGTGAGATCAAACTGAATAGAAGC
AATGAGGCCACCGGTTTAAATGGAAATGACGGCAAAAACGAAACTTTCGGCATTGTTAGCGAAGGGAGCTTCATGCCTGA
TACCAGCGAGTGGAAAAAAGTATTGCTGCCTTGGACGGTTCGGGGTTTTGCTGATGACAGTAAATTTAAAGAATTCAACA
AAGAAGAAAAAAACAACGACAACAAGCCAAAATACAGCCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAGCGCAAT
TTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGGGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATAT
CTTCAAAAAAGGCAACGGCGGGGACGAGCGCAACTATAGTCTGAAGCTCAGTTATATCCCGGGCACGATGCCGCGCAAGA
ATATTGAAAACAACGACTCCACCCTCGCCAAAGAGCTGCGCGCCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGC
GTGGACGGCGGCTTTGTCTTGCGCCAAGTTAACAACTTAAATGGGCAAGACCGCGTGTTTATGTTCGGCGCGATGGGCTT
TGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCA
AAAATGACAAGAATAGCAATAACGGCGTGGAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGC
AAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGAAATTACCAGCGGCGACAATAAAACCGCGCTGTATGTGTA
TGATTTGGAAGGAAACGGTACGAATAATCTGATTAAAAAAATCGAAGTACCCGGTGGCAAGGGCGGGCTTTCGTCCCCCA
CGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGAT
TTGAGCAGTCAAGATCCTAAACAATGGTCTGCACGCGCCATTTTTAAAGGCGACAAACCGATTACTTCCGCGCCCGCCAT
TTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTACTCAGTACGAGCG
AACAATATATTTACGGTATCTTCGACGACGATACGGCGGCGAGTAATGTAGATGTAAAACTCAAAGGTTTGGGAGGCGGG
TTGCTCGAGCAGGTGCTTGAGCAGAAGGATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACGGATCGGGCAATAA
GGGCTGGGTAGTGAAATTGAAGGACGGACAGCGCGTTACCGTCAAGCCGACCGTGGTATTGCGTACCGCCTTTGTAACCA
TCCATAAATATACGGGTACGGACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTG
ACCAAGAAAAGCGCGCGCCCGATTGTGCCGGAAGCCAATCAGGCTGTCGCGCAATATTCCGGTCATAAGAAAACCGCCAA
CGGCAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGG
TTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGTATA
GACCCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGCACCCTGCTGATGAACGATTT
GGACAGCTTGGACATTACCGGCCCGATGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(481-816)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

79.724

100

0.803

Multiple sequence alignment