Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV179_RS10940 Genome accession   NZ_CP031331
Coordinates   1825300..1828338 (+) Length   1012 a.a.
NCBI ID   WP_322114703.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M26263     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1820300..1833338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV179_RS10895 - 1820349..1820669 (-) 321 WP_002216895.1 DUF1132 family protein -
  DV179_RS10900 - 1820788..1821087 (-) 300 WP_024464993.1 hypothetical protein -
  DV179_RS10905 - 1821115..1821345 (-) 231 WP_002223585.1 hypothetical protein -
  DV179_RS10910 - 1821583..1821783 (-) 201 WP_002218476.1 hypothetical protein -
  DV179_RS10915 - 1821787..1822098 (-) 312 WP_002218477.1 hypothetical protein -
  DV179_RS10920 - 1822110..1823324 (-) 1215 WP_002220395.1 replication initiation factor domain-containing protein -
  DV179_RS10935 - 1824474..1824758 (+) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  DV179_RS14670 pilC 1825199..1825321 (+) 123 WP_306808222.1 hypothetical protein Machinery gene
  DV179_RS10940 pilC 1825300..1828338 (+) 3039 WP_322114703.1 PilC family type IV pilus tip adhesin Machinery gene
  DV179_RS10970 yccS 1830722..1832872 (-) 2151 WP_024465005.1 YccS family putative transporter -

Sequence

Protein


Download         Length: 1012 a.a.        Molecular weight: 110858.70 Da        Isoelectric Point: 9.6321

>NTDB_id=305896 DV179_RS10940 WP_322114703.1 1825300..1828338(+) (pilC) [Neisseria meningitidis strain M26263]
MYSYSIVMNGQKLPEVKNGNQGNQRNQRQATFTTNFSRVKKNTTFTFNNTDDVVAQKSSTVVFGTATYLPPYGKVSGFDE
NGLKERGDAVGWIGTTHPGLIGYSYQGNTCSSGDCPELSYKTQFTFGHQGLKKKTGGKLDIDADKSRDNSPIYKLSDNSW
LGVSFNLSSESTAESKQNKKLVSSFSENVTQSNGTQGQNKDKNLVYNTDNQRHNNNNRVNQNSSHAVAFYLNAKLHLLDK
KQINNIAQGVTVDLGTLKTRIEPTDEWKNKRYLTFVVNQWEFKDAGSVSVKLKLPEVKAGRCINKPNPNNHTKAPSPALT
APALWFGPVQNGKAEMYSASVSTYPDSSSSRIFLQNLKRKTDPGRPGRYSLADLSASDIQSKEPTFTSRQTIIRLDKGVH
QIKLQGNEVANFNGNDGKNDTFGIVSEGSFMPDTSEWKKVLLPWTVRGFSNDNEFAKFNKESDKYSQRYRIRDNNGNRNL
GDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDTSALKDSTLAKELRTFAEKGYVGD
RYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLTKADSNNPTAVSLFDVKNGNNSNNSNNSVQLGYTVGTPQ
IGKTHNGKYAAFLASGYATKTIDDQQNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGN
MYRFDLSSDNPSSWTVRTIFSGNKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDKTDEQYIYGIFDDDTVATGSVNFSG
TGGGLLEQVLSVENKTLFLTDYKRSDGSGSKGWVVKLKEGQRVTVKPTVVLRTAFVTIRKYKDNGCGAETAILGINTADG
GKLTKKSARPIVPADNTAVAQYSGHKQTTKGKSIPIGCMEKDNGIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGG
SGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3039 bp        

>NTDB_id=305896 DV179_RS10940 WP_322114703.1 1825300..1828338(+) (pilC) [Neisseria meningitidis strain M26263]
ATGTATTCATACAGTATTGTAATGAACGGACAAAAGCTGCCCGAAGTAAAGAATGGGAACCAAGGCAATCAACGCAATCA
ACGCCAAGCTACCTTTACGACAAATTTTAGTAGAGTCAAAAAAAACACTACTTTCACATTCAATAATACCGATGATGTTG
TTGCTCAAAAAAGCAGCACTGTCGTTTTTGGTACAGCCACCTACCTGCCGCCCTACGGCAAGGTTTCTGGTTTTGATGAA
AACGGGCTGAAAGAACGCGGCGATGCCGTTGGTTGGATTGGTACGACCCACCCGGGGTTGATAGGCTACAGCTACCAAGG
TAACACATGCAGCAGCGGAGACTGTCCTGAACTTAGCTATAAAACCCAATTTACCTTCGGTCATCAAGGGTTGAAAAAAA
AGACAGGCGGCAAGCTGGATATAGACGCAGACAAAAGCCGCGACAATTCGCCCATTTACAAATTGTCGGATAATTCTTGG
TTGGGCGTGTCTTTCAATTTGAGCAGCGAGAGCACCGCCGAATCAAAGCAAAACAAGAAATTGGTATCTTCTTTTAGCGA
GAACGTGACGCAGAGCAATGGTACGCAAGGACAAAACAAAGACAAAAACCTCGTGTATAACACGGACAATCAACGTCATA
ATAATAATAATCGTGTCAATCAGAACAGCAGCCACGCCGTCGCCTTTTATCTGAACGCCAAGCTGCACCTGCTGGATAAA
AAACAAATCAACAATATCGCGCAAGGCGTAACAGTTGATTTGGGTACCTTGAAAACGCGCATCGAGCCGACGGACGAGTG
GAAGAATAAGAGGTATCTCACTTTCGTTGTTAATCAGTGGGAGTTCAAAGATGCCGGATCAGTCAGCGTCAAACTCAAAT
TGCCGGAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATAATCATACCAAAGCCCCTTCGCCGGCACTGACT
GCCCCCGCGCTGTGGTTCGGACCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCTACCTACCCCGACAG
TTCGAGCAGCCGCATCTTCCTTCAAAATCTGAAAAGAAAAACCGACCCCGGCAGACCCGGCCGCTATTCCCTCGCAGACT
TGAGTGCGTCGGATATTCAAAGTAAAGAGCCGACTTTCACAAGTCGGCAAACAATCATCCGATTGGATAAAGGCGTACAT
CAGATCAAACTTCAAGGCAATGAGGTCGCCAATTTTAATGGAAATGACGGCAAAAACGACACTTTCGGCATTGTTAGTGA
AGGGAGCTTCATGCCTGATACCAGCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTTTTAGTAATGACAATG
AATTTGCAAAATTCAACAAAGAATCAGACAAATACAGCCAAAGATACCGCATCCGCGACAACAACGGCAATCGCAATTTG
GGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTT
CAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTG
ATAACGACACTTCCGCTCTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGAC
CGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGG
TGCGATGGGCCTGGGCGGCAGAGGCGCGTATGCCTTGGATTTGACCAAAGCCGACAGCAATAACCCGACCGCCGTTTCCC
TGTTTGATGTCAAAAATGGCAATAATAGCAATAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAA
ATCGGCAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACCATTGACGACCAACAAAA
TAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCG
GGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAAT
ATGTACCGCTTTGATTTGAGCAGCGACAATCCGTCCAGCTGGACTGTACGCACTATTTTCAGCGGCAACAAACCGATTAC
TTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAGGATGATG
TTGATAAAACGGACGAACAATATATTTACGGTATCTTTGACGACGATACGGTGGCGACGGGTTCTGTAAACTTCAGCGGT
ACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAGTGTGGAAAATAAAACCTTATTCCTGACCGATTATAAGCGATCCGACGG
ATCGGGCAGTAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCG
CTTTCGTAACCATCCGCAAATATAAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGC
GGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCCGACAATACGGCTGTCGCGCAATATTCCGGCCATAAGCA
AACCACCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACG
ACAAACCGGTTAATGTGCGTTATCTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGC
AGCGGAACATTCAAAGAAGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGAT
GAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(480-820)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

70.708

100

0.72

Multiple sequence alignment