Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXE32_RS16060 Genome accession   NZ_CP035850
Coordinates   3340282..3340938 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TW10590     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3335282..3345938
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXE32_RS16030 dcyD 3336162..3337148 (+) 987 WP_001128223.1 D-cysteine desulfhydrase -
  EXE32_RS16035 tcyL 3337163..3337831 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EXE32_RS16040 tcyN 3337828..3338580 (+) 753 WP_001273007.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EXE32_RS16045 sdiA 3338810..3339532 (+) 723 WP_001154285.1 transcriptional regulator SdiA -
  EXE32_RS16050 yecF 3339599..3339823 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EXE32_RS16055 yecU 3339810..3339986 (-) 177 WP_000590347.1 protein YecU -
  EXE32_RS26990 - 3340069..3340140 (-) 72 Protein_3140 transcriptional regulator -
  EXE32_RS16060 letA 3340282..3340938 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EXE32_RS16065 uvrC 3340935..3342767 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EXE32_RS16070 pgsA 3342824..3343372 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EXE32_RS16090 yecA 3344022..3344687 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=305840 EXE32_RS16060 WP_000611335.1 3340282..3340938(+) (letA) [Escherichia coli strain TW10590]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=305840 EXE32_RS16060 WP_000611335.1 3340282..3340938(+) (letA) [Escherichia coli strain TW10590]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment