Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   DV163_RS08610 Genome accession   NZ_CP031330
Coordinates   1458977..1459351 (-) Length   124 a.a.
NCBI ID   WP_009348628.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M21955     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1438533..1465589 1458977..1459351 within 0


Gene organization within MGE regions


Location: 1438533..1465589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV163_RS08520 oatC 1438533..1439915 (-) 1383 WP_002247492.1 capsular polysaccharide O-acetyltransferase OatC -
  DV163_RS08525 - 1439944..1441422 (-) 1479 WP_115437308.1 alpha-2,8-polysialyltransferase family protein -
  DV163_RS08530 siaC 1441502..1442551 (-) 1050 WP_002248654.1 polysialic acid capsule biosynthesis protein SiaC -
  DV163_RS08535 neuA 1442552..1443238 (-) 687 WP_002215295.1 N-acylneuraminate cytidylyltransferase -
  DV163_RS08540 neuC 1443242..1444375 (-) 1134 WP_115437309.1 UDP-N-acetylglucosamine 2-epimerase -
  DV163_RS08545 ctrA 1444502..1445677 (+) 1176 WP_021438836.1 capsule polysaccharide export outer membrane protein CtrA -
  DV163_RS08550 ctrB 1445692..1446855 (+) 1164 WP_002215287.1 capsule polysaccharide export protein CtrB -
  DV163_RS08555 - 1446855..1447652 (+) 798 WP_014575090.1 ABC transporter permease -
  DV163_RS08560 - 1447649..1448299 (+) 651 WP_002218516.1 ABC transporter ATP-binding protein -
  DV163_RS08565 - 1448363..1450636 (+) 2274 WP_115437310.1 Tex family protein -
  DV163_RS08570 dcm 1450667..1451497 (+) 831 WP_002215283.1 DNA (cytosine-5-)-methyltransferase -
  DV163_RS14175 - 1451475..1451669 (+) 195 WP_002215282.1 DNA cytosine methyltransferase -
  DV163_RS08575 - 1451662..1452006 (+) 345 WP_002231447.1 DNA adenine methylase -
  DV163_RS08580 galE 1452085..1452705 (+) 621 Protein_1419 UDP-glucose 4-epimerase GalE -
  DV163_RS08585 rfbB 1452706..1453789 (+) 1084 Protein_1420 dTDP-glucose 4,6-dehydratase -
  DV163_RS08590 rfbA 1453852..1454718 (+) 867 WP_002224369.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DV163_RS08595 rfbC 1454772..1455329 (+) 558 WP_002220108.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  DV163_RS08600 - 1455373..1457391 (-) 2019 WP_002224746.1 oligopeptide transporter, OPT family -
  DV163_RS08605 dnaJ 1457587..1458708 (-) 1122 WP_002215274.1 molecular chaperone DnaJ -
  DV163_RS08610 comE 1458977..1459351 (-) 375 WP_009348628.1 ComEA family DNA-binding protein Machinery gene
  DV163_RS08650 dksA 1465173..1465589 (-) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 124 a.a.        Molecular weight: 13444.25 Da        Isoelectric Point: 10.9392

>NTDB_id=305841 DV163_RS08610 WP_009348628.1 1458977..1459351(-) (comE) [Neisseria meningitidis strain M21955]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 375 bp        

>NTDB_id=305841 DV163_RS08610 WP_009348628.1 1458977..1459351(-) (comE) [Neisseria meningitidis strain M21955]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGGCTTCCGTCGG
CGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694
  comE Neisseria gonorrhoeae MS11

70.492

98.387

0.694

Multiple sequence alignment