Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA02_RS12030 Genome accession   NZ_CP035841
Coordinates   2462612..2463202 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain TW10722     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2457612..2468202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA02_RS12000 emrD 2458094..2459278 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  EXA02_RS12005 ysdE 2459360..2459434 (+) 75 WP_211180519.1 protein YsdE -
  EXA02_RS12010 tisB 2459697..2459786 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EXA02_RS12015 ivbL 2460351..2460449 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EXA02_RS12020 ilvB 2460555..2462243 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EXA02_RS12025 ilvN 2462247..2462537 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EXA02_RS12030 letA 2462612..2463202 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EXA02_RS12035 uhpB 2463202..2464704 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EXA02_RS12040 uhpC 2464714..2466033 (+) 1320 WP_001355850.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EXA02_RS12045 uhpT 2466171..2467562 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=305646 EXA02_RS12030 WP_000633668.1 2462612..2463202(+) (letA) [Escherichia coli strain TW10722]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=305646 EXA02_RS12030 WP_000633668.1 2462612..2463202(+) (letA) [Escherichia coli strain TW10722]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378