Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXA03_RS15585 Genome accession   NZ_CP035836
Coordinates   3155380..3155970 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain WS1933D     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3150380..3160970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA03_RS15570 uhpT 3151020..3152411 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  EXA03_RS15575 uhpC 3152549..3153868 (-) 1320 WP_000936563.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EXA03_RS15580 uhpB 3153878..3155380 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EXA03_RS15585 letA 3155380..3155970 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EXA03_RS15590 ilvN 3156045..3156335 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  EXA03_RS15595 ilvB 3156339..3158027 (-) 1689 WP_000168460.1 acetolactate synthase large subunit -
  EXA03_RS15600 ivbL 3158133..3158231 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  EXA03_RS15605 tisB 3158796..3158885 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EXA03_RS15610 ysdE 3159009..3159083 (-) 75 WP_211180519.1 protein YsdE -
  EXA03_RS15615 emrD 3159165..3160349 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  EXA03_RS15620 yidF 3160357..3160854 (-) 498 WP_000148063.1 radical SAM protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=305573 EXA03_RS15585 WP_000633668.1 3155380..3155970(-) (letA) [Escherichia coli strain WS1933D]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=305573 EXA03_RS15585 WP_000633668.1 3155380..3155970(-) (letA) [Escherichia coli strain WS1933D]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment