Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EXA03_RS13775 Genome accession   NZ_CP035836
Coordinates   2752610..2753242 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain WS1933D     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2747610..2758242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA03_RS13750 yheS 2747779..2749692 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  EXA03_RS13755 yheT 2749692..2750714 (+) 1023 WP_000057357.1 hydrolase -
  EXA03_RS13760 yheU 2750708..2750926 (+) 219 WP_000907085.1 YheU family protein -
  EXA03_RS13765 prkB 2750980..2751849 (+) 870 WP_001274680.1 phosphoribulokinase -
  EXA03_RS13770 yhfA 2751904..2752308 (-) 405 WP_001148908.1 OsmC family protein -
  EXA03_RS13775 crp 2752610..2753242 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EXA03_RS13780 yhfK 2753293..2755383 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EXA03_RS13785 argD 2755450..2756670 (-) 1221 WP_000963787.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EXA03_RS13790 pabA 2756756..2757319 (-) 564 WP_000601851.1 aminodeoxychorismate synthase component 2 -
  EXA03_RS13795 fic 2757351..2757953 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EXA03_RS13800 yhfG 2757943..2758110 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=305563 EXA03_RS13775 WP_000242755.1 2752610..2753242(+) (crp) [Escherichia coli strain WS1933D]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=305563 EXA03_RS13775 WP_000242755.1 2752610..2753242(+) (crp) [Escherichia coli strain WS1933D]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467