Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EXA06_RS15035 Genome accession   NZ_CP035822
Coordinates   3059542..3060174 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain WS4437A-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3054542..3065174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA06_RS15010 yheS 3054711..3056624 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  EXA06_RS15015 yheT 3056624..3057646 (+) 1023 WP_000057356.1 hydrolase -
  EXA06_RS15020 yheU 3057640..3057858 (+) 219 WP_000907085.1 YheU family protein -
  EXA06_RS15025 prkB 3057912..3058781 (+) 870 WP_001274680.1 phosphoribulokinase -
  EXA06_RS15030 yhfA 3058836..3059240 (-) 405 WP_001414096.1 OsmC family protein -
  EXA06_RS15035 crp 3059542..3060174 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EXA06_RS15040 yhfK 3060225..3062315 (+) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  EXA06_RS15045 argD 3062382..3063602 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EXA06_RS15050 pabA 3063688..3064251 (-) 564 WP_001737557.1 aminodeoxychorismate synthase component 2 -
  EXA06_RS15055 fic 3064283..3064885 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EXA06_RS15060 yhfG 3064875..3065042 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=305315 EXA06_RS15035 WP_000242755.1 3059542..3060174(+) (crp) [Escherichia coli strain WS4437A-1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=305315 EXA06_RS15035 WP_000242755.1 3059542..3060174(+) (crp) [Escherichia coli strain WS4437A-1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment