Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DWB91_RS04350 Genome accession   NZ_CP031266
Coordinates   911156..911785 (+) Length   209 a.a.
NCBI ID   WP_037566926.1    Uniprot ID   -
Organism   Staphylococcus agnetis strain 12B     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 906156..916785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DWB91_RS04320 (DWB91_04325) - 906472..907503 (-) 1032 WP_145051473.1 aromatic acid exporter family protein -
  DWB91_RS04325 (DWB91_04330) - 907623..907940 (-) 318 WP_261370712.1 YkvA family protein -
  DWB91_RS04330 (DWB91_04335) map 908169..908927 (+) 759 WP_060551430.1 type I methionyl aminopeptidase -
  DWB91_RS04335 (DWB91_04340) - 909026..909412 (+) 387 WP_086375153.1 hypothetical protein -
  DWB91_RS04340 (DWB91_04345) liaF 909425..910126 (+) 702 WP_060551429.1 cell wall-active antibiotics response protein LiaF -
  DWB91_RS04345 (DWB91_04350) vraS 910123..911166 (+) 1044 WP_037566929.1 sensor histidine kinase Regulator
  DWB91_RS04350 (DWB91_04355) vraR 911156..911785 (+) 630 WP_037566926.1 response regulator transcription factor Regulator
  DWB91_RS04355 (DWB91_04360) - 911851..912420 (-) 570 WP_037566924.1 carbonic anhydrase -
  DWB91_RS04360 (DWB91_04365) - 912456..913727 (-) 1272 WP_060551427.1 YihY/virulence factor BrkB family protein -
  DWB91_RS04365 (DWB91_04370) - 913843..914118 (-) 276 WP_037566921.1 hypothetical protein -
  DWB91_RS04370 (DWB91_04375) - 914126..914584 (-) 459 WP_060551426.1 low molecular weight protein-tyrosine-phosphatase -
  DWB91_RS04375 (DWB91_04380) - 914717..914926 (+) 210 WP_145051476.1 DUF1128 domain-containing protein -
  DWB91_RS04380 (DWB91_04385) - 914943..916178 (+) 1236 WP_060551424.1 aminopeptidase -
  DWB91_RS04385 (DWB91_04390) - 916191..916709 (+) 519 WP_060551423.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23591.31 Da        Isoelectric Point: 5.1805

>NTDB_id=305254 DWB91_RS04350 WP_037566926.1 911156..911785(+) (vraR) [Staphylococcus agnetis strain 12B]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAISKAHELKPDLILMDLVMTDMDGVEATTQIKKELPRIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSAKDIAEAIRKTFQGESVFEAEVLVKMRNRMRQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=305254 DWB91_RS04350 WP_037566926.1 911156..911785(+) (vraR) [Staphylococcus agnetis strain 12B]
ATGACAATTAAAGTATTATTTGTAGATGATCATGAAATGGTTAGAATTGGAATTTCGAGTTATCTTTCTACACAACCAGA
CATTGAAGTAGTAGGTGAAGGGGCGTCAGGTAAAGAGGCAATCTCAAAAGCACATGAACTGAAACCGGATTTAATTTTAA
TGGATTTAGTGATGACAGATATGGATGGGGTTGAGGCTACGACACAAATTAAAAAAGAGTTACCACGTATCAAAGTGGTG
ATGCTTACAAGTTACATTGAGGATAAAGAAGTTTATCGCGCTTTAGATGCCGGTGTCGACAGCTATATTTTAAAAACAAC
AAGTGCAAAAGATATTGCCGAAGCTATTCGTAAAACATTCCAAGGTGAATCTGTTTTTGAAGCAGAAGTATTAGTGAAAA
TGCGAAATCGTATGCGACAAAGAGCTGAACTTTACGAATTGTTAACGGAACGTGAAATGGAAATTTTATTGCTGATTTCC
AAAGGGTATTCGAATCAAGAAATTGCGAGCGCTTCACATATTACGATTAAGACTGTAAAAACTCATGTGAGTAATATTTT
AAGTAAATTGGAAGTTCAGGACCGTACTCAGGCTGTGATATATGCCTTTCAACATGGGTTAATAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.909

100

0.909
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment