Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EXA07_RS11230 Genome accession   NZ_CP035819
Coordinates   2286292..2286924 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain WS3294A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2281292..2291924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA07_RS11205 yheS 2281461..2283374 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  EXA07_RS11210 yheT 2283374..2284396 (+) 1023 WP_000057405.1 hydrolase -
  EXA07_RS11215 yheU 2284390..2284608 (+) 219 WP_000907085.1 YheU family protein -
  EXA07_RS11220 prkB 2284662..2285531 (+) 870 WP_001274680.1 phosphoribulokinase -
  EXA07_RS11225 yhfA 2285586..2285990 (-) 405 WP_001148913.1 OsmC family protein -
  EXA07_RS11230 crp 2286292..2286924 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EXA07_RS11235 yhfK 2286975..2289065 (+) 2091 WP_216350968.1 YccS/YhfK family putative transporter -
  EXA07_RS11240 argD 2289132..2290352 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EXA07_RS11245 pabA 2290438..2291001 (-) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EXA07_RS11250 fic 2291033..2291635 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EXA07_RS11255 yhfG 2291625..2291792 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=305224 EXA07_RS11230 WP_000242755.1 2286292..2286924(+) (crp) [Escherichia coli strain WS3294A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=305224 EXA07_RS11230 WP_000242755.1 2286292..2286924(+) (crp) [Escherichia coli strain WS3294A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment