Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV401_RS01175 Genome accession   NZ_CP031254
Coordinates   242017..242691 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain M25588     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 237017..247691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV401_RS01155 hinT 238721..239071 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  DV401_RS01160 - 239071..239421 (+) 351 WP_005647993.1 YcfL family protein -
  DV401_RS01165 nagZ 239425..240477 (+) 1053 WP_071163125.1 beta-N-acetylhexosaminidase -
  DV401_RS01170 rlmC 240474..241652 (+) 1179 WP_071163124.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV401_RS01175 crp 242017..242691 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV401_RS01180 - 242676..242927 (-) 252 WP_005647999.1 YheU family protein -
  DV401_RS01185 slmA 242949..243605 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  DV401_RS01190 dut 243609..244064 (-) 456 WP_005631431.1 dUTP diphosphatase -
  DV401_RS01195 coaBC 244112..245314 (-) 1203 WP_071163123.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV401_RS01200 radC 245477..246169 (+) 693 WP_114877181.1 RadC family protein -
  DV401_RS01205 rpmB 246383..246619 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV401_RS01210 rpmG 246631..246801 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=305081 DV401_RS01175 WP_005647998.1 242017..242691(-) (crp) [Haemophilus influenzae strain M25588]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=305081 DV401_RS01175 WP_005647998.1 242017..242691(-) (crp) [Haemophilus influenzae strain M25588]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment