Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EXA09_RS07270 Genome accession   NZ_CP035812
Coordinates   1577592..1578224 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain B7A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1572592..1583224
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXA09_RS07245 yhfG 1572724..1572891 (+) 168 WP_000736860.1 YhfG family protein -
  EXA09_RS07250 fic 1572881..1573483 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  EXA09_RS07255 pabA 1573515..1574078 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  EXA09_RS07260 argD 1574164..1575384 (+) 1221 WP_001297516.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EXA09_RS07265 yhfK 1575451..1577541 (-) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  EXA09_RS07270 crp 1577592..1578224 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EXA09_RS07275 yhfA 1578526..1578930 (+) 405 WP_001148908.1 OsmC family protein -
  EXA09_RS07280 prkB 1578985..1579854 (-) 870 WP_001274680.1 phosphoribulokinase -
  EXA09_RS07285 yheU 1579908..1580126 (-) 219 WP_000907085.1 YheU family protein -
  EXA09_RS07290 yheT 1580120..1581142 (-) 1023 WP_000057405.1 hydrolase -
  EXA09_RS07295 yheS 1581142..1583055 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=305061 EXA09_RS07270 WP_000242755.1 1577592..1578224(-) (crp) [Escherichia coli strain B7A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=305061 EXA09_RS07270 WP_000242755.1 1577592..1578224(-) (crp) [Escherichia coli strain B7A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment