Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV389_RS01030 Genome accession   NZ_CP031250
Coordinates   209788..210462 (-) Length   224 a.a.
NCBI ID   WP_112102720.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M21384     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 204788..215462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV389_RS01010 (DV389_01010) - 206495..206845 (+) 351 WP_005686227.1 HIT domain-containing protein -
  DV389_RS01015 (DV389_01015) - 206845..207195 (+) 351 WP_114892869.1 DUF1425 domain-containing protein -
  DV389_RS01020 (DV389_01020) nagZ 207199..208251 (+) 1053 WP_114892870.1 beta-N-acetylhexosaminidase -
  DV389_RS01025 (DV389_01025) rlmC 208248..209435 (+) 1188 WP_032824528.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV389_RS01030 (DV389_01030) crp 209788..210462 (-) 675 WP_112102720.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV389_RS01035 (DV389_01035) - 210447..210698 (-) 252 WP_032824522.1 YheU family protein -
  DV389_RS01040 (DV389_01040) slmA 210721..211377 (-) 657 WP_114892871.1 nucleoid occlusion factor SlmA -
  DV389_RS01045 (DV389_01045) dut 211381..211836 (-) 456 WP_044330861.1 dUTP diphosphatase -
  DV389_RS01050 (DV389_01050) coaBC 212151..213365 (-) 1215 WP_050846690.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV389_RS01055 (DV389_01055) radC 213528..214193 (+) 666 WP_114892872.1 DNA repair protein RadC -
  DV389_RS01060 (DV389_01060) rpmB 214406..214642 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV389_RS01065 (DV389_01065) rpmG 214654..214824 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25104.79 Da        Isoelectric Point: 6.6042

>NTDB_id=304934 DV389_RS01030 WP_112102720.1 209788..210462(-) (crp) [Haemophilus influenzae strain M21384]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEVGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304934 DV389_RS01030 WP_112102720.1 209788..210462(-) (crp) [Haemophilus influenzae strain M21384]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGTGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTAATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.536

100

0.955
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment