Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   DV378_RS04655 Genome accession   NZ_CP031249
Coordinates   940732..941241 (-) Length   169 a.a.
NCBI ID   WP_050948870.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M15895     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 935732..946241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV378_RS04625 nfuA 936282..936878 (-) 597 WP_021034385.1 Fe-S biogenesis protein NfuA -
  DV378_RS04630 - 936954..937640 (-) 687 WP_050948865.1 ComF family protein -
  DV378_RS04635 tnpA 937999..938454 (-) 456 WP_050948866.1 IS200/IS605 family transposase -
  DV378_RS04640 comE 938451..939794 (-) 1344 WP_050948867.1 type IV pilus secretin PilQ Machinery gene
  DV378_RS04645 comD 939804..940217 (-) 414 WP_050948868.1 pilus assembly protein PilP Machinery gene
  DV378_RS04650 comC 940214..940735 (-) 522 WP_050948869.1 competence protein ComC Machinery gene
  DV378_RS04655 comB 940732..941241 (-) 510 WP_050948870.1 hypothetical protein Machinery gene
  DV378_RS04660 comA 941242..942039 (-) 798 WP_050948871.1 pilus assembly protein PilM Machinery gene
  DV378_RS04665 - 942138..944738 (+) 2601 WP_050948872.1 penicillin-binding protein 1A -
  DV378_RS04670 - 944815..945660 (+) 846 WP_005652116.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  DV378_RS04675 - 945813..946142 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -

Sequence

Protein


Download         Length: 169 a.a.        Molecular weight: 19976.93 Da        Isoelectric Point: 9.3342

>NTDB_id=304917 DV378_RS04655 WP_050948870.1 940732..941241(-) (comB) [Haemophilus influenzae strain M15895]
MSMNLLPWRTYQHQNRLRRLAFYIALFILLAINLTLAFSNLIEQQKQDLQAQQTSFEQLNQQLYKTAKKIEQLRSAVQVG
EILTSIPKEQVKKSLQRLSELPFQQGELNKFKQDAHNLSLEGLAQDQREFELIHQFLKKHFPNVKLSQFQPEQQSLYFLF
DVEQVGEDK

Nucleotide


Download         Length: 510 bp        

>NTDB_id=304917 DV378_RS04655 WP_050948870.1 940732..941241(-) (comB) [Haemophilus influenzae strain M15895]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAACCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAACTTTGGCTTTTAGTAATTTAATTGAACAACAAAAACAAGATCTGCAAGCGCAGCAAA
CATCTTTTGAACAACTTAATCAGCAACTTTATAAAACCGCCAAGAAAATTGAACAGTTGCGTAGTGCAGTGCAGGTTGGC
GAAATTTTGACATCTATTCCTAAAGAGCAAGTAAAAAAGAGTTTACAGCGGCTAAGTGAATTACCTTTTCAGCAAGGAGA
ACTGAATAAATTTAAACAAGATGCTCATAACTTAAGTTTGGAAGGTCTCGCACAAGATCAAAGAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGCCAGTTTCAACCTGAACAACAGTCATTGTATTTTCTCTTT
GATGTGGAACAAGTTGGAGAAGATAAGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

86.826

98.817

0.858
  comB Haemophilus influenzae Rd KW20

85.629

98.817

0.846

Multiple sequence alignment