Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV378_RS01875 Genome accession   NZ_CP031249
Coordinates   394467..395141 (-) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain M15895     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 389467..400141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV378_RS01855 hinT 391174..391524 (+) 351 WP_005651576.1 purine nucleoside phosphoramidase -
  DV378_RS01860 - 391524..391874 (+) 351 WP_032824530.1 DUF1425 domain-containing protein -
  DV378_RS01865 nagZ 391878..392930 (+) 1053 WP_050948671.1 beta-N-acetylhexosaminidase -
  DV378_RS01870 rlmC 392927..394114 (+) 1188 WP_050948672.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV378_RS01875 crp 394467..395141 (-) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV378_RS01880 - 395126..395377 (-) 252 WP_032824522.1 YheU family protein -
  DV378_RS01885 slmA 395400..396056 (-) 657 WP_050948673.1 nucleoid occlusion factor SlmA -
  DV378_RS01890 dut 396060..396515 (-) 456 WP_044330861.1 dUTP diphosphatase -
  DV378_RS01895 coaBC 397205..398419 (-) 1215 WP_050948674.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV378_RS01900 radC 398582..399247 (+) 666 WP_050846688.1 DNA repair protein RadC -
  DV378_RS01905 rpmB 399461..399697 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV378_RS01910 rpmG 399709..399879 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=304899 DV378_RS01875 WP_032824524.1 394467..395141(-) (crp) [Haemophilus influenzae strain M15895]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304899 DV378_RS01875 WP_032824524.1 394467..395141(-) (crp) [Haemophilus influenzae strain M15895]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATTCTCACTTACTTAGGT
GCAGGACAATTTTTTGGAGAAGCGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment