Detailed information NTG0304799

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: DV129_RS09465
• Genome accession: NZ_CP031247
• Coordinates: 1738993..1740003 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain M23734
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1733993..1745003

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DV129_RS09435	-	1734863..1735069 (+)	207	WP_000503437.1	hypothetical protein	-
DV129_RS09440	-	1735066..1735260 (+)	195	WP_000820179.1	hypothetical protein	-
DV129_RS09445	-	1735247..1736131 (+)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
DV129_RS09450	-	1736133..1736870 (+)	738	WP_000832838.1	ABC transporter permease	-
DV129_RS09455	-	1736870..1737967 (+)	1098	WP_000893543.1	sensor histidine kinase	-
DV129_RS09460	-	1737969..1738568 (+)	600	WP_000866726.1	response regulator transcription factor	-
DV129_RS09465	ccpA	1738993..1740003 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
DV129_RS09470	-	1740067..1740483 (+)	417	WP_114865989.1	hypothetical protein	-
DV129_RS09475	-	1740480..1741442 (-)	963	WP_001124777.1	asparaginase	-
DV129_RS09480	-	1741508..1742896 (+)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
DV129_RS09485	-	1742931..1743383 (-)	453	WP_000079154.1	universal stress protein	-
DV129_RS09490	-	1743545..1743838 (+)	294	WP_000977367.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=304799 DV129_RS09465 WP_000990607.1 1738993..1740003(+) (ccpA) [Streptococcus pneumoniae strain M23734]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=304799 DV129_RS09465 WP_000990607.1 1738993..1740003(+) (ccpA) [Streptococcus pneumoniae strain M23734]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568