Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ECE110019_RS12705 Genome accession   NZ_CP035751
Coordinates   2559619..2560275 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli E110019     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2554619..2565275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECE110019_RS12675 yecA 2555870..2556535 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  ECE110019_RS12695 pgsA 2557185..2557733 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ECE110019_RS12700 uvrC 2557790..2559622 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  ECE110019_RS12705 letA 2559619..2560275 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  ECE110019_RS27785 - 2560417..2560488 (+) 72 Protein_2531 transcriptional regulator -
  ECE110019_RS12710 yecU 2560571..2560747 (+) 177 WP_000590347.1 protein YecU -
  ECE110019_RS12715 yecF 2560734..2560958 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  ECE110019_RS12720 sdiA 2561025..2561747 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  ECE110019_RS12725 tcyN 2561977..2562729 (-) 753 Protein_2535 L-cystine ABC transporter ATP-binding protein TcyN -
  ECE110019_RS12730 tcyL 2562726..2563394 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  ECE110019_RS12735 dcyD 2563409..2564395 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=304579 ECE110019_RS12705 WP_000611335.1 2559619..2560275(-) (letA) [Escherichia coli E110019]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=304579 ECE110019_RS12705 WP_000611335.1 2559619..2560275(-) (letA) [Escherichia coli E110019]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment