Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV428_RS04000 Genome accession   NZ_CP031243
Coordinates   779300..779977 (-) Length   225 a.a.
NCBI ID   WP_005633332.1    Uniprot ID   -
Organism   Haemophilus haemolyticus strain M19346     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 774300..784977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV428_RS03980 hinT 776001..776351 (+) 351 WP_114908761.1 purine nucleoside phosphoramidase -
  DV428_RS03985 - 776351..776701 (+) 351 WP_114908762.1 DUF1425 domain-containing protein -
  DV428_RS03990 nagZ 776705..777757 (+) 1053 WP_114908763.1 beta-N-acetylhexosaminidase -
  DV428_RS03995 rlmC 777754..778932 (+) 1179 WP_114908764.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV428_RS04000 crp 779300..779977 (-) 678 WP_005633332.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV428_RS04005 - 779962..780213 (-) 252 WP_005631427.1 YheU family protein -
  DV428_RS04010 slmA 780235..780891 (-) 657 WP_005636931.1 nucleoid occlusion factor SlmA -
  DV428_RS04015 dut 780895..781350 (-) 456 WP_005631431.1 dUTP diphosphatase -
  DV428_RS04020 coaBC 781398..782600 (-) 1203 WP_114908765.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV428_RS04025 radC 782764..783429 (+) 666 WP_005631435.1 DNA repair protein RadC -
  DV428_RS04030 rpmB 783643..783879 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV428_RS04035 rpmG 783891..784061 (+) 171 WP_005613503.1 50S ribosomal protein L33 -
  DV428_RS04040 mutM 784133..784948 (+) 816 WP_114908766.1 DNA-formamidopyrimidine glycosylase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25266.94 Da        Isoelectric Point: 6.6051

>NTDB_id=304576 DV428_RS04000 WP_005633332.1 779300..779977(-) (crp) [Haemophilus haemolyticus strain M19346]
MSNELTEIDEVVTSSQEEETTQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSAKDDEGKEMILTYL
GAGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIA
QTLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=304576 DV428_RS04000 WP_005633332.1 779300..779977(-) (crp) [Haemophilus haemolyticus strain M19346]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGAGACAACTCAACGAGATCCAGTTTT
AGATTGGTTTCTTACTCACTGCCATTTACATAAATATCCCGCAAAATCGACTTTAATTCACGCAGGTGAAGATGCAACGA
CACTTTATTATGTCATTAAAGGCTCTGTAATGGTGTCAGCAAAAGATGATGAAGGTAAAGAGATGATTCTCACTTATTTG
GGGGCAGGACAATTCTTTGGTGAAGCTGGATTATTTGATGAAGGTTCAAAACGATCTGCTTGGGTAAAAACAAAAACAAC
ATGTGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCG
CACAACTGGCTAGACGTTTACAAAATACTTCACGCCAAGTCAGTAACCTTGCATTCTTAGATGTGGCAGGCCGTATTGCT
CAAACGCTAATGAACTTAGCTAAACAGCCTGACGCAATGACACATCCTGATGGGATGCAAATCAAAATTACACGTCAAGA
AATAGGGCAAATGGTGGGTTGTTCACGAGAAACTGTAGGACGCATTATTAAAATGTTAGAGGATCAGAATCTTATCCACG
CTCATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(37-125)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(157-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

97.778

100

0.978
  crp Vibrio cholerae strain A1552

75.98

90.667

0.689
  crp Acinetobacter baumannii D1279779

47.668

85.778

0.409

Multiple sequence alignment