Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DV390_RS07545 Genome accession   NZ_CP031242
Coordinates   1494790..1496007 (+) Length   405 a.a.
NCBI ID   WP_014550481.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M21460     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1489790..1501007
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV390_RS07525 corC 1490757..1491656 (-) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -
  DV390_RS07530 ampD 1492278..1492838 (-) 561 WP_011271974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DV390_RS07535 pilA 1492953..1493402 (+) 450 WP_011271973.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DV390_RS07540 - 1493399..1494793 (+) 1395 Protein_1452 GspE/PulE family protein -
  DV390_RS07545 pilC 1494790..1496007 (+) 1218 WP_014550481.1 type II secretion system F family protein Machinery gene
  DV390_RS07550 pilD 1496004..1496696 (+) 693 WP_014550482.1 prepilin peptidase Machinery gene
  DV390_RS07555 rho 1496750..1498012 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  DV390_RS07560 metJ 1498260..1498577 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DV390_RS07565 cueR 1498591..1498977 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DV390_RS07570 - 1499054..1499260 (+) 207 WP_005666692.1 heavy-metal-associated domain-containing protein -
  DV390_RS07575 - 1499346..1499552 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV390_RS07580 - 1499626..1499832 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DV390_RS07585 - 1499906..1500112 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46089.34 Da        Isoelectric Point: 9.9010

>NTDB_id=304547 DV390_RS07545 WP_014550481.1 1494790..1496007(+) (pilC) [Haemophilus influenzae strain M21460]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=304547 DV390_RS07545 WP_014550481.1 1494790..1496007(+) (pilC) [Haemophilus influenzae strain M21460]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTA
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACAAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTACCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

98.03

100

0.983
  pilC Haemophilus influenzae Rd KW20

96.798

100

0.97
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment