Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV390_RS03760 Genome accession   NZ_CP031242
Coordinates   768575..769249 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain M21460     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 763575..774249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV390_RS03740 hinT 765277..765627 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  DV390_RS03745 - 765627..765977 (+) 351 WP_005647993.1 YcfL family protein -
  DV390_RS03750 nagZ 765981..767036 (+) 1056 WP_042593724.1 beta-N-acetylhexosaminidase -
  DV390_RS03755 rlmC 767029..768210 (+) 1182 WP_042593723.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV390_RS03760 crp 768575..769249 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV390_RS03765 - 769234..769485 (-) 252 WP_005647999.1 YheU family protein -
  DV390_RS03770 slmA 769507..770163 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  DV390_RS03775 dut 770167..770622 (-) 456 WP_005631431.1 dUTP diphosphatase -
  DV390_RS03780 coaBC 770670..771872 (-) 1203 WP_011272308.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV390_RS03785 radC 772035..772700 (+) 666 WP_013526173.1 RadC family protein -
  DV390_RS03790 rpmB 772914..773150 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV390_RS03795 rpmG 773162..773332 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=304523 DV390_RS03760 WP_005647998.1 768575..769249(-) (crp) [Haemophilus influenzae strain M21460]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304523 DV390_RS03760 WP_005647998.1 768575..769249(-) (crp) [Haemophilus influenzae strain M21460]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment