Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV384_RS08810 Genome accession   NZ_CP031241
Coordinates   1775926..1776600 (+) Length   224 a.a.
NCBI ID   WP_110426323.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M17648     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770926..1781600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV384_RS08775 rpmG 1771842..1772012 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  DV384_RS08780 rpmB 1772024..1772260 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV384_RS08785 radC 1772474..1773139 (-) 666 WP_013527272.1 DNA repair protein RadC -
  DV384_RS08790 coaBC 1773303..1774505 (+) 1203 WP_114890555.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV384_RS08795 dut 1774553..1775008 (+) 456 WP_005631431.1 dUTP diphosphatase -
  DV384_RS08800 slmA 1775012..1775668 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  DV384_RS08805 - 1775690..1775941 (+) 252 WP_005647999.1 YheU family protein -
  DV384_RS08810 crp 1775926..1776600 (+) 675 WP_110426323.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV384_RS08815 rlmC 1776965..1778143 (-) 1179 WP_114890554.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV384_RS08820 nagZ 1778136..1779191 (-) 1056 WP_114934712.1 beta-N-acetylhexosaminidase -
  DV384_RS08825 - 1779195..1779545 (-) 351 WP_005647993.1 DUF1425 domain-containing protein -
  DV384_RS08830 hinT 1779545..1779895 (-) 351 WP_005655947.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25181.88 Da        Isoelectric Point: 6.8375

>NTDB_id=304517 DV384_RS08810 WP_110426323.1 1775926..1776600(+) (crp) [Haemophilus influenzae strain M17648]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304517 DV384_RS08810 WP_110426323.1 1775926..1776600(+) (crp) [Haemophilus influenzae strain M17648]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATTAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGGTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCACAAGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

99.554

100

0.996
  crp Vibrio cholerae strain A1552

75.98

91.071

0.692
  crp Acinetobacter baumannii D1279779

48.718

87.054

0.424

Multiple sequence alignment