Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV369_RS03065 Genome accession   NZ_CP031239
Coordinates   603619..604293 (+) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain M13034     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 598619..609293
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV369_RS03030 rpmG 598881..599051 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  DV369_RS03035 rpmB 599063..599299 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV369_RS03040 radC 599513..600178 (-) 666 WP_050846688.1 DNA repair protein RadC -
  DV369_RS03045 coaBC 600341..601555 (+) 1215 WP_050948674.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV369_RS03050 dut 602245..602700 (+) 456 WP_044330861.1 dUTP diphosphatase -
  DV369_RS03055 slmA 602704..603360 (+) 657 WP_050948673.1 nucleoid occlusion factor SlmA -
  DV369_RS03060 - 603383..603634 (+) 252 WP_032824522.1 YheU family protein -
  DV369_RS03065 crp 603619..604293 (+) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV369_RS03070 rlmC 604644..605831 (-) 1188 WP_050948672.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV369_RS03075 nagZ 605828..606880 (-) 1053 WP_050948671.1 beta-N-acetylhexosaminidase -
  DV369_RS03080 - 606884..607234 (-) 351 WP_032824530.1 DUF1425 domain-containing protein -
  DV369_RS03085 hinT 607234..607584 (-) 351 WP_005651576.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=304435 DV369_RS03065 WP_032824524.1 603619..604293(+) (crp) [Haemophilus influenzae strain M13034]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304435 DV369_RS03065 WP_032824524.1 603619..604293(+) (crp) [Haemophilus influenzae strain M13034]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATTCTCACTTACTTAGGT
GCAGGACAATTTTTTGGAGAAGCGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment