Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV441_RS06675 Genome accession   NZ_CP031238
Coordinates   1380829..1381506 (-) Length   225 a.a.
NCBI ID   WP_046953328.1    Uniprot ID   A0A0M3G6A8
Organism   Haemophilus haemolyticus strain M28486     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1375829..1386506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV441_RS06655 hinT 1377532..1377882 (+) 351 WP_032803248.1 purine nucleoside phosphoramidase -
  DV441_RS06660 - 1377882..1378232 (+) 351 WP_114892579.1 YcfL family protein -
  DV441_RS06665 nagZ 1378236..1379288 (+) 1053 WP_114892580.1 beta-N-acetylhexosaminidase -
  DV441_RS06670 rlmC 1379285..1380463 (+) 1179 WP_114892581.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV441_RS06675 crp 1380829..1381506 (-) 678 WP_046953328.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV441_RS06680 - 1381491..1381742 (-) 252 WP_005631427.1 YheU family protein -
  DV441_RS06685 slmA 1381764..1382420 (-) 657 WP_005627377.1 nucleoid occlusion factor SlmA -
  DV441_RS06690 dut 1382424..1382879 (-) 456 WP_005627376.1 dUTP diphosphatase -
  DV441_RS06695 coaBC 1382927..1384129 (-) 1203 WP_046953327.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV441_RS06700 radC 1384293..1384958 (+) 666 WP_046953326.1 RadC family protein -
  DV441_RS06705 rpmB 1385172..1385408 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV441_RS06710 rpmG 1385420..1385590 (+) 171 WP_005613503.1 50S ribosomal protein L33 -
  DV441_RS06715 mutM 1385662..1386477 (+) 816 WP_046953325.1 DNA-formamidopyrimidine glycosylase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25263.98 Da        Isoelectric Point: 6.3843

>NTDB_id=304408 DV441_RS06675 WP_046953328.1 1380829..1381506(-) (crp) [Haemophilus haemolyticus strain M28486]
MSNELTELDEVVTSSQEEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSAKDDEGKEMILTYL
GAGEFFGEAGLFDEGSKRSAWVKTKTICEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIA
QTLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=304408 DV441_RS06675 WP_046953328.1 1380829..1381506(-) (crp) [Haemophilus haemolyticus strain M28486]
ATGTCAAATGAATTAACCGAACTTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGAGGCAACTCAACGAGATCCAGTTTT
AGATTGGTTTCTTACTCACTGCCATTTACATAAATATCCCGCAAAATCGACTTTAATTCACGCAGGTGAAGATGCAACGA
CACTTTATTATGTCATTAAAGGCTCTGTAATGGTGTCAGCAAAAGATGATGAAGGTAAAGAGATGATTCTCACTTATTTG
GGTGCAGGAGAATTCTTTGGTGAAGCAGGATTGTTTGATGAAGGATCAAAACGCTCTGCTTGGGTAAAAACAAAAACAAT
ATGTGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCG
CACAATTGGCAAGACGTTTACAAAATACTTCACGCCAAGTCAGTAATTTAGCATTCTTAGATGTCGCAGGCCGTATTGCT
CAAACGCTAATGAACTTAGCTAAACAGCCTGAAGCAATGACACATCCTGATGGGATGCAAATCAAAATTACACGTCAAGA
AATAGGGCAAATGGTTGGTTGTTCACGAGAAACTGTAGGACGTATTATTAAGATGTTAGAAGATCAGAATCTTATCCACG
CTCATGGAAAAACCATTGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(37-125)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(157-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M3G6A8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

97.333

100

0.973
  crp Vibrio cholerae strain A1552

75.49

90.667

0.684
  crp Acinetobacter baumannii D1279779

48.187

85.778

0.413

Multiple sequence alignment