Detailed information
Bioinformatically predicted
Overview
| Name | comD | Type | Machinery gene |
| Locus tag | DV441_RS04980 | Genome accession | NZ_CP031238 |
| Coordinates | 1038709..1039122 (+) | Length | 137 a.a. |
| NCBI ID | WP_046953214.1 | Uniprot ID | A0A0M3G6S1 |
| Organism | Haemophilus haemolyticus strain M28486 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
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Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1011422..1047175 | 1038709..1039122 | within | 0 |
Gene organization within MGE regions
Location: 1011422..1047175
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DV441_RS04805 | mutY | 1011422..1012558 (+) | 1137 | WP_046953237.1 | A/G-specific adenine glycosylase | - |
| DV441_RS04810 | - | 1012536..1012808 (+) | 273 | WP_005625838.1 | oxidative damage protection protein | - |
| DV441_RS04815 | mltC | 1012823..1013899 (+) | 1077 | WP_046953236.1 | membrane-bound lytic murein transglycosylase MltC | - |
| DV441_RS04830 | - | 1015230..1016420 (+) | 1191 | WP_046953234.1 | phage major capsid protein | - |
| DV441_RS04835 | - | 1016465..1017031 (+) | 567 | WP_046953233.1 | HK97 family phage prohead protease | - |
| DV441_RS04840 | - | 1017033..1018265 (+) | 1233 | WP_046953232.1 | phage portal protein | - |
| DV441_RS04845 | - | 1018249..1018593 (+) | 345 | WP_046953231.1 | phage head closure protein | - |
| DV441_RS04850 | - | 1018580..1018888 (+) | 309 | WP_046953230.1 | head-tail connector protein | - |
| DV441_RS04855 | - | 1018905..1019267 (+) | 363 | WP_046953229.1 | HNH endonuclease signature motif containing protein | - |
| DV441_RS04860 | - | 1019369..1019743 (+) | 375 | WP_005626376.1 | phage terminase small subunit P27 family | - |
| DV441_RS04865 | - | 1019751..1021418 (+) | 1668 | WP_046953228.1 | terminase large subunit | - |
| DV441_RS04870 | - | 1021739..1022026 (+) | 288 | WP_230599552.1 | hypothetical protein | - |
| DV441_RS04875 | - | 1022224..1022607 (+) | 384 | WP_046953227.1 | hypothetical protein | - |
| DV441_RS04880 | - | 1022708..1023547 (+) | 840 | WP_046953226.1 | hypothetical protein | - |
| DV441_RS04885 | - | 1023719..1023940 (+) | 222 | WP_005760675.1 | helix-turn-helix transcriptional regulator | - |
| DV441_RS04890 | - | 1024030..1024629 (+) | 600 | WP_230599549.1 | host cell division inhibitor Icd-like protein | - |
| DV441_RS04895 | - | 1024622..1024870 (+) | 249 | WP_046953225.1 | hypothetical protein | - |
| DV441_RS04900 | - | 1024863..1025063 (+) | 201 | WP_046953224.1 | hypothetical protein | - |
| DV441_RS04905 | - | 1025053..1025259 (+) | 207 | WP_005629564.1 | hypothetical protein | - |
| DV441_RS04910 | - | 1025246..1025794 (+) | 549 | WP_046953223.1 | hypothetical protein | - |
| DV441_RS04915 | - | 1025802..1026239 (+) | 438 | WP_046953240.1 | hypothetical protein | - |
| DV441_RS04920 | - | 1026223..1027991 (+) | 1769 | Protein_935 | DNA primase family protein | - |
| DV441_RS04925 | - | 1028163..1029389 (-) | 1227 | WP_046953221.1 | tyrosine-type recombinase/integrase | - |
| DV441_RS04935 | secG | 1029688..1030026 (-) | 339 | WP_046939867.1 | preprotein translocase subunit SecG | - |
| DV441_RS04940 | - | 1030135..1032090 (-) | 1956 | WP_046953220.1 | DNA topoisomerase III | - |
| DV441_RS04945 | recR | 1032106..1032708 (-) | 603 | WP_005626527.1 | recombination mediator RecR | - |
| DV441_RS04950 | - | 1032771..1033100 (-) | 330 | WP_005629464.1 | YbaB/EbfC family nucleoid-associated protein | - |
| DV441_RS04955 | - | 1033268..1034113 (-) | 846 | WP_046953219.1 | 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ | - |
| DV441_RS04960 | - | 1034187..1036787 (-) | 2601 | WP_046953218.1 | penicillin-binding protein 1A | - |
| DV441_RS04965 | comA | 1036887..1037666 (+) | 780 | WP_114892495.1 | competence protein ComA | Machinery gene |
| DV441_RS04970 | comB | 1037685..1038194 (+) | 510 | WP_046953216.1 | competence protein B | Machinery gene |
| DV441_RS04975 | comC | 1038191..1038712 (+) | 522 | WP_046953215.1 | competence protein ComC | Machinery gene |
| DV441_RS04980 | comD | 1038709..1039122 (+) | 414 | WP_046953214.1 | pilus assembly protein PilP | Machinery gene |
| DV441_RS04985 | comE | 1039132..1040475 (+) | 1344 | WP_114892496.1 | type IV pilus secretin PilQ family protein | Machinery gene |
| DV441_RS04990 | tnpA | 1040472..1040927 (+) | 456 | WP_005626546.1 | IS200/IS605 family transposase | - |
| DV441_RS04995 | - | 1041129..1041815 (+) | 687 | WP_005626547.1 | ComF family protein | - |
| DV441_RS05000 | nfuA | 1041891..1042487 (+) | 597 | WP_005626550.1 | Fe-S biogenesis protein NfuA | - |
| DV441_RS05005 | nudC | 1042556..1043353 (+) | 798 | WP_005626553.1 | NAD(+) diphosphatase | - |
| DV441_RS05010 | - | 1043386..1043976 (+) | 591 | WP_005626555.1 | YjaG family protein | - |
| DV441_RS05015 | - | 1044114..1044386 (+) | 273 | WP_005626557.1 | HU family DNA-binding protein | - |
| DV441_RS05020 | - | 1044514..1045287 (+) | 774 | WP_005626560.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| DV441_RS05025 | glmS | 1045343..1047175 (+) | 1833 | WP_005626562.1 | glutamine--fructose-6-phosphate transaminase (isomerizing) | - |
Sequence
Protein
Download Length: 137 a.a. Molecular weight: 15593.71 Da Isoelectric Point: 4.4237
>NTDB_id=304398 DV441_RS04980 WP_046953214.1 1038709..1039122(+) (comD) [Haemophilus haemolyticus strain M28486]
MKYWFYLIILFFMNCSWGQDPFDKTQRTHSQFDNAQTVMEQTEIISSDVPNNLCGADENRQAAEIPLNALKLVGVVISKD
KAFALLLDQDLQIYSVLEGVDVAQEGYVVTKINQNKVQFMRKSGAQCDSTEQKELSF
MKYWFYLIILFFMNCSWGQDPFDKTQRTHSQFDNAQTVMEQTEIISSDVPNNLCGADENRQAAEIPLNALKLVGVVISKD
KAFALLLDQDLQIYSVLEGVDVAQEGYVVTKINQNKVQFMRKSGAQCDSTEQKELSF
Nucleotide
Download Length: 414 bp
>NTDB_id=304398 DV441_RS04980 WP_046953214.1 1038709..1039122(+) (comD) [Haemophilus haemolyticus strain M28486]
ATGAAATATTGGTTTTACCTGATTATATTATTTTTTATGAATTGCAGTTGGGGACAAGATCCTTTCGATAAAACACAGCG
TACCCATTCTCAGTTTGATAACGCACAAACAGTAATGGAGCAGACAGAAATAATTTCCTCAGATGTACCTAATAATCTAT
GCGGAGCTGATGAAAATCGCCAAGCAGCTGAAATTCCTTTGAACGCTTTAAAATTGGTGGGCGTAGTGATTTCTAAAGAT
AAAGCGTTTGCGTTATTGCTGGATCAGGATTTGCAAATTTACAGCGTTTTAGAGGGCGTTGATGTAGCTCAAGAAGGATA
TGTTGTAACAAAAATCAATCAAAATAAAGTTCAATTTATGCGTAAGTCTGGTGCTCAATGTGATAGTACTGAACAGAAAG
AATTAAGTTTTTAA
ATGAAATATTGGTTTTACCTGATTATATTATTTTTTATGAATTGCAGTTGGGGACAAGATCCTTTCGATAAAACACAGCG
TACCCATTCTCAGTTTGATAACGCACAAACAGTAATGGAGCAGACAGAAATAATTTCCTCAGATGTACCTAATAATCTAT
GCGGAGCTGATGAAAATCGCCAAGCAGCTGAAATTCCTTTGAACGCTTTAAAATTGGTGGGCGTAGTGATTTCTAAAGAT
AAAGCGTTTGCGTTATTGCTGGATCAGGATTTGCAAATTTACAGCGTTTTAGAGGGCGTTGATGTAGCTCAAGAAGGATA
TGTTGTAACAAAAATCAATCAAAATAAAGTTCAATTTATGCGTAAGTCTGGTGCTCAATGTGATAGTACTGAACAGAAAG
AATTAAGTTTTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comD | Haemophilus influenzae 86-028NP |
89.781 |
100 |
0.898 |
| comD | Haemophilus influenzae Rd KW20 |
89.051 |
100 |
0.891 |