Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV365_RS06655 Genome accession   NZ_CP031237
Coordinates   1363711..1364385 (-) Length   224 a.a.
NCBI ID   WP_110426323.1    Uniprot ID   -
Organism   Haemophilus influenzae strain M12125     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1358711..1369385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV365_RS06635 hinT 1360416..1360766 (+) 351 WP_114890551.1 purine nucleoside phosphoramidase -
  DV365_RS06640 - 1360766..1361116 (+) 351 WP_114890552.1 DUF1425 domain-containing protein -
  DV365_RS06645 nagZ 1361120..1362175 (+) 1056 WP_114890553.1 beta-N-acetylhexosaminidase -
  DV365_RS06650 rlmC 1362168..1363346 (+) 1179 WP_114890554.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV365_RS06655 crp 1363711..1364385 (-) 675 WP_110426323.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV365_RS06660 - 1364370..1364621 (-) 252 WP_005647999.1 YheU family protein -
  DV365_RS06665 slmA 1364643..1365299 (-) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  DV365_RS06670 dut 1365303..1365758 (-) 456 WP_005631431.1 dUTP diphosphatase -
  DV365_RS06675 coaBC 1365806..1367008 (-) 1203 WP_114890555.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV365_RS06680 radC 1367172..1367837 (+) 666 WP_013527272.1 DNA repair protein RadC -
  DV365_RS06685 rpmB 1368051..1368287 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV365_RS06690 rpmG 1368299..1368469 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25181.88 Da        Isoelectric Point: 6.8375

>NTDB_id=304369 DV365_RS06655 WP_110426323.1 1363711..1364385(-) (crp) [Haemophilus influenzae strain M12125]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304369 DV365_RS06655 WP_110426323.1 1363711..1364385(-) (crp) [Haemophilus influenzae strain M12125]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAGTATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATTAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGGTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCACAAGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

99.554

100

0.996
  crp Vibrio cholerae strain A1552

75.98

91.071

0.692
  crp Acinetobacter baumannii D1279779

48.718

87.054

0.424

Multiple sequence alignment