Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   DV400_RS07755 Genome accession   NZ_CP031236
Coordinates   1569784..1570458 (-) Length   224 a.a.
NCBI ID   WP_032824524.1    Uniprot ID   A0A0K9L2I4
Organism   Haemophilus influenzae strain M25267     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1564784..1575458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV400_RS07735 hinT 1566491..1566841 (+) 351 WP_005651576.1 purine nucleoside phosphoramidase -
  DV400_RS07740 - 1566841..1567191 (+) 351 WP_032824530.1 DUF1425 domain-containing protein -
  DV400_RS07745 nagZ 1567195..1568247 (+) 1053 WP_050948671.1 beta-N-acetylhexosaminidase -
  DV400_RS07750 rlmC 1568244..1569431 (+) 1188 WP_050948672.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  DV400_RS07755 crp 1569784..1570458 (-) 675 WP_032824524.1 cAMP-activated global transcriptional regulator CRP Regulator
  DV400_RS07760 - 1570443..1570694 (-) 252 WP_032824522.1 YheU family protein -
  DV400_RS07765 slmA 1570717..1571373 (-) 657 WP_050948673.1 nucleoid occlusion factor SlmA -
  DV400_RS07770 dut 1571377..1571832 (-) 456 WP_044330861.1 dUTP diphosphatase -
  DV400_RS07775 coaBC 1572522..1573736 (-) 1215 WP_050948674.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  DV400_RS07780 radC 1573899..1574564 (+) 666 WP_050846688.1 DNA repair protein RadC -
  DV400_RS07785 rpmB 1574778..1575014 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  DV400_RS07790 rpmG 1575026..1575196 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25076.74 Da        Isoelectric Point: 6.6042

>NTDB_id=304336 DV400_RS07755 WP_032824524.1 1569784..1570458(-) (crp) [Haemophilus influenzae strain M25267]
MSNELTEVDDVVTSPQEETTPNDPILDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIAQ
TLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=304336 DV400_RS07755 WP_032824524.1 1569784..1570458(-) (crp) [Haemophilus influenzae strain M25267]
ATGTCAAATGAATTAACTGAAGTTGATGATGTTGTAACATCTCCGCAGGAAGAAACAACACCGAATGATCCCATTTTAGA
TTGGTTTCTTACCCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCACGCAGGGGAAGATGCGACTACGT
TGTATTATGTAATTAAAGGCTCTGTAATGGTGTCTTCAAAAGATGATGAAGGCAAAGAGATGATTCTCACTTACTTAGGT
GCAGGACAATTTTTTGGAGAAGCGGGATTATTTGATGAGGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTAAGTAACCTTGCATTCTTAGATGTAGCAGGGCGTATCGCTCAA
ACACTGATGAATTTAGCTAAACAACCCGATGCAATGACCCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGGGAAACTGTGGGACGAATTATCAAGATGTTAGAGGATCAGAACCTTATTCATGCCC
ATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9L2I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

95.982

100

0.96
  crp Vibrio cholerae strain A1552

73.364

95.536

0.701
  crp Acinetobacter baumannii D1279779

47.668

86.161

0.411

Multiple sequence alignment